Life Sciences Commons^™

Physical Activity And Exercise For Hot Flashes: Trigger Or Treatment?, Sarah Witkowski, Rose Evard, Jacquelyn J. Rickson, Quinn White, Lynnette Leidy Sievert

Exercise and Sport Studies: Faculty Publications

Importance and Objective: Hot flashes (HFs) are a prevalent feature of menopause. Hot flashes can be bothersome and affect quality of life. However, HFs have also been associated with the risk for cardiovascular disease. Therefore, providing current evidence on the effect of therapies to reduce HFs can help patients and providers with decision making. This review provides details on the scientific evidence to date related to the effect of physical activity (PA) and exercise to alter the HF experience in women

Methods: The PubMed database was searched between June 2020 and June 2022 for currently available evidence regarding the relation …

Circulating Angiogenic Cell Population Responses To 10 Days Of Reduced Physical Activity, Gayatri Guhanarayan, Julianne Jablonski, Sarah Witkowski

Exercise and Sport Studies: Faculty Publications

Circulating angiogenic cells (CACs) are a diverse group that have been identified as predictors of cardiovascular health and are inversely proportional to cardiovascular disease (CVD) outcomes. Inactivity is a growing concern in industrialized nations and is an independent risk factor for CVD. There is limited evidence regarding the impact of reduced physical activity (rPA) on different CAC populations. The purpose of this study was to evaluate the effect of objectively monitored rPA with maintained energy balance on two CAC populations (CFU and CD34+cells), intracellular nitric oxide (NOi), and genes related to NO production in active, healthy men. Participants (age 25 …

Relationship Between Circulating Progenitor Cells, Vascular Function And Oxidative Stress With Long-Term Training And Short-Term Detraining In Older Men, Sarah Witkowski, Michael M. Lockard, Nathan T. Jenkins, Thomas O. Obisesan, Espen E. Spangenburg, James M. Hagberg

Exercise and Sport Studies: Faculty Publications

Exercise may contribute to the maintenance of vascular function via enhanced liberation and action of bone-marrow-derived progenitor cells. Activity related changes in oxidative stress may also influence the number and function of these cells. In the present study, we sought to determine (i) whether adaptations in reactive hyperaemic FBF (forearm blood flow) response associated with long-term endurance exercise and short-term detraining were related to resting putative progenitor cell number and function, and (ii) whether oxidative stress affected these factors. Participants included men with a history of more than 30 years of moderate-to-high-intensity exercise (HI group) and healthy low-active age- and …

Exercise, Apoe, And Working Memory: Meg And Behavioral Evidence For Benefit Of Exercise In Epsilon4 Carriers, Sean P. Deeny, David Poeppel, Jo B. Zimmerman, Stephen M. Roth, Josef Brandauer, Sarah Witkowski, Joseph W. Hearn, Andrew T. Ludlow, José L. Contreras-Vidal, Jason Brandt, Bradley D. Hatfield

Exercise and Sport Studies: Faculty Publications

Performance on the Sternberg working memory task, and MEG cortical response on a variation of the Sternberg task were examined in middle-aged carriers and non-carriers of the APOE ε4 allele. Physical activity was also assessed to examine whether exercise level modifies the relationship between APOE genotype and neurocognitive function. Regression revealed that high physical activity was associated with faster RT in the six- and eight-letter conditions of the Sternberg in ε4 carriers, but not in the non-carriers after controlling for age, gender, and education (N = 54). Furthermore, the MEG analysis revealed that sedentary ε4 carriers exhibited lower right temporal …