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Neurobehavioral And Gene Expression Effects Of Early Embryonic Methylmercury Exposure In Yellow Perch (Perca Flavescens) And Zebrafish (Danio Rerio) Larvae, Francisco Xavier Mora Zamorano
Neurobehavioral And Gene Expression Effects Of Early Embryonic Methylmercury Exposure In Yellow Perch (Perca Flavescens) And Zebrafish (Danio Rerio) Larvae, Francisco Xavier Mora Zamorano
Theses and Dissertations
Methylmercury (MeHg) is a pervasive and persistent neurotoxic environmental pollutant known to affect the behavior of fish, birds and mammals. The present study addresses the neurobehavioral and gene expression effects of MeHg in yellow perch (Perca flavescens) and zebrafish (Danio rerio) embryos. The rationale for this study originated from an interest to understand the behavioral and molecular phenotypes of environmental MeHg exposure in the yellow perch, an ecologically and economically relevant species of the North American Great Lakes region. Both MeHg and the yellow perch coexist in a common ecosystem: the North American Great Lakes. However, the effects of this …
Female Reproductive Impacts Of Dietary Methylmercury In Yellow Perch (Perca Flavescens) And Zebrafish (Danio Rerio), Abigail Rachael Debofsky
Female Reproductive Impacts Of Dietary Methylmercury In Yellow Perch (Perca Flavescens) And Zebrafish (Danio Rerio), Abigail Rachael Debofsky
Theses and Dissertations
This study sought to evaluate the effects of dietary MeHg exposure on female teleost reproduction and phenotypically-anchor gene dysregulation in adult yellow perch (Perca flavescens) and zebrafish (Danio rerio) in order to establish relevant biomarkers relating exposure and subsequent reproductive effects. Yellow perch were used in the study for their socioeconomic importance within the Great Lakes basin, and their significance to the food web. Utilization of zebrafish allowed for a detailed analysis of the molecular effects of MeHg and established its relevance as a model for other fish species. MeHg exposures at environmentally relevant levels were done in zebrafish for …