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The Role Of Environmental Filtering In Structuring Appalachian Tree Communities: Topographic Influences On Functional Diversity Are Mediated Through Soil Characteristics, Julia I. Chapman, Ryan W. Mcewan Jan 2018

The Role Of Environmental Filtering In Structuring Appalachian Tree Communities: Topographic Influences On Functional Diversity Are Mediated Through Soil Characteristics, Julia I. Chapman, Ryan W. Mcewan

Ryan McEwan

Identifying the drivers of community assembly has long been a central goal in ecology, and the development of functional diversity indices has provided a new way of detecting the influence of environmental gradients on biotic communities. For an old-growth Appalachian forest, we used path analysis to understand how patterns of tree functional diversity relate to topography and soil gradients and to determine whether topographic effects are mediated through soil chemistry. All of our path models supported the idea of environmental filtering: stressful areas (high elevation, low soil moisture, low soil nutrients) were occupied by communities of low functional diversity, which …


Assessing Public Health Burden Associated With Exposure To Ambient Black Carbon In The United States, Ying Li, Daven K. Henze, Darby Jack, Barron H. Henderson, Patrick L. Kinney Apr 2017

Assessing Public Health Burden Associated With Exposure To Ambient Black Carbon In The United States, Ying Li, Daven K. Henze, Darby Jack, Barron H. Henderson, Patrick L. Kinney

Ying Li

Black carbon (BC) is a significant component of fine particulate matter (PM2.5) air pollution, which has been linked to a series of adverse health effects, in particular premature mortality. Recent scientific research indicates that BC also plays an important role in climate change. Therefore, controlling black carbon emissions provides an opportunity for a double dividend. This study quantifies the national burden of mortality and morbidity attributable to exposure to ambient BC in the United States (US). We use GEOS–Chem, a global 3-D model of atmospheric composition to estimate the 2010 annual average BC levels at 0.5 x 0.667° resolution, and …


Winter Rye Cover Crop Biomass Production, Degradation, And N Recycling, J. L. Pantoja, J. E. Sawyer, D. W. Barker Apr 2017

Winter Rye Cover Crop Biomass Production, Degradation, And N Recycling, J. L. Pantoja, J. E. Sawyer, D. W. Barker

John E. Sawyer

Winter rye (Secale cereale L.) as a cover crop can take up residual inorganic N between annual row crops and therefore be used to help reduce NO3 -–N loss from fields and movement to water systems. However, does the rye N uptake affect N recycling to soil and add to plant available N? The rye carbon:nitrogen (C:N) ratio could also influence N recycling. The objectives of this study were to evaluate rye biomass degradation and N recycling after spring rye termination in a no-till corn (Zea mays L.) - soybean [Glycine max. (L.) Merr.] rotation. A two year experiment (2010-2011) …


Disease Will Limit Future Food Supply From The Global Crustacean Fishery And Aquaculture Sectors, G. Stentiford, D. Neil, E. Peeler, J. Shields, H. Small, T. Flegel, J. Vlak, B. Jones, F. Morado, S. Moss, J. Lotz, Lyric Bartholomay, D. Behringer, C. Hauton, D. Lightner Dec 2015

Disease Will Limit Future Food Supply From The Global Crustacean Fishery And Aquaculture Sectors, G. Stentiford, D. Neil, E. Peeler, J. Shields, H. Small, T. Flegel, J. Vlak, B. Jones, F. Morado, S. Moss, J. Lotz, Lyric Bartholomay, D. Behringer, C. Hauton, D. Lightner

Lyric Bartholomay

Seafood is a highly traded food commodity. Farmed and captured crustaceans contribute a significant proportion with annual production exceeding 10 M metric tonnes with first sale value of $40bn. The sector is dominated by farmed tropical marine shrimp, the fastest growing sector of the global aquaculture industry. It is significant in supporting rural livelihoods and alleviating poverty in producing nations within Asia and Latin America while forming an increasing contribution to aquatic food supply in more developed countries. Nations with marine borders often also support important marine fisheries for crustaceans that are regionally traded as live animals and commodity products. …


The Impacts Of Climate Change Mitigation Strategies On Animal Welfare, Sara Shields, Geoffrey Orme-Evans Jun 2015

The Impacts Of Climate Change Mitigation Strategies On Animal Welfare, Sara Shields, Geoffrey Orme-Evans

Sara Shields, PhD

The objective of this review is to point out that the global dialog on reducing greenhouse gas emissions in animal agriculture has, thus far, not adequately considered animal welfare in proposed climate change mitigation strategies. Many suggested approaches for reducing emissions, most of which could generally be described as calls for the intensification of production, can have substantial effects on the animals. Given the growing world-wide awareness and concern for animal welfare, many of these approaches are not socially sustainable. This review identifies the main emission abatement strategies in the climate change literature that would negatively affect animal welfare and …


Video Feature — Banned Books And The Stuart Rose Collection, Robert Brecha, Una Cadegan, John Inglis, Paul Morman Feb 2015

Video Feature — Banned Books And The Stuart Rose Collection, Robert Brecha, Una Cadegan, John Inglis, Paul Morman

Robert J. Brecha

A faculty panel discussion in two sessions:

Session 1:
The Index: Una Cadegan (history) looks at the current scholarship on the Index of Forbidden Books.
Galileo: Robert Brecha (physics) highlights the banning of Galileo and observational science.

Session 2:
Thomas Aquinas: John Inglis (philosophy) speaks on the banning of Thomas Aquinas's Summa Theologica, the most important book in Catholic intellectual tradition.
Descartes and the Index of Forbidden Books: Paul Morman (history, Distinguished Service Professor) highlights the book by Descartes that he was not allowed to study while a student at UD in the 1960s.


Advancing Computational Toxicology In A Regulatory Setting: A Selected Review Of The Accomplishments Of Gilman D. Veith (1944–2013), Steven P. Bradbury, Christine L. Russom, Patricia K. Schmieder, Terry W. Schultz, Robert Diderich, Charles M. Auer Jan 2015

Advancing Computational Toxicology In A Regulatory Setting: A Selected Review Of The Accomplishments Of Gilman D. Veith (1944–2013), Steven P. Bradbury, Christine L. Russom, Patricia K. Schmieder, Terry W. Schultz, Robert Diderich, Charles M. Auer

Steven P. Bradbury

With the passing of Dr. Gilman D. Veith on August 18, 2013, the research community lost one of its true visionaries in the development and implementation of alternative in silico and in vitro toxicology models in human health and ecological risk assessment. His career spanned more than four decades, during which he repeatedly demonstrated vision and leadership to advance alternative testing and assessment research and to guide the adoption of research accomplishments into U.S. and international chemical regulatory programs. His ability to advance toxicological and environmental exposure research, and associated quantitative structure– activity relationships (QSARs), for application in environmental regulatory …


Use Of Geographical Information Systems To Identify Counties In Georgia With High Risk For Childhood Lead Poisoning, R. Christopher Rustin, Christy Kuriatnyk, Byron Lobsinger, Simone Charles Dec 2014

Use Of Geographical Information Systems To Identify Counties In Georgia With High Risk For Childhood Lead Poisoning, R. Christopher Rustin, Christy Kuriatnyk, Byron Lobsinger, Simone Charles

R. Christopher Rustin

Background: For children in Georgia, lead poisoning is a substantial public health problem. Primary risk factors include low socioeconomic status and poor-quality housing built prior to 1978. The Environmental Health Team of the Georgia Department of Public Health (DPH) utilized geographical information system (GIS) technology and census housing data to identify counties in which children have high risk for lead poisoning. The purpose of this research was to update and refine previous maps developed with older technology and on a different geographic scale so that targeted public health interventions can be developed.

Methods: Data related to stratified and …


An Evaluation Of The Us High Production Volume (Hpv) Chemical-Testing Programme: A Study In (Ir)Relevance, Redundancy And Retro Thinking, Andrew Nicholson, Jessica Sandler, Troy Seidle Dec 2014

An Evaluation Of The Us High Production Volume (Hpv) Chemical-Testing Programme: A Study In (Ir)Relevance, Redundancy And Retro Thinking, Andrew Nicholson, Jessica Sandler, Troy Seidle

Troy Seidle, PhD

Under the US Environmental Protection Agency (EPA) High Production Volume (HPV) Challenge Programme, chemical companies have volunteered to conduct screening-level toxicity tests on approximately 2800 widely-used industrial chemicals. Participating companies are committed to providing available toxicity information to the EPA and presenting testing proposals for review by the EPA and posting on the EPA Web site as public information. People for the Ethical Treatment of Animals (PETA) and a coalition of animal protection organisations have reviewed all the test plans submitted by the participating chemical companies for compliance with the original HPV framework, as well as with animal welfare guidelines …


A Modular One-Generation Reproduction Study As A Flexible Testing System For Regulatory Safety Assessment, Richard Vogel, Troy Seidle, Horst Spielmann Dec 2014

A Modular One-Generation Reproduction Study As A Flexible Testing System For Regulatory Safety Assessment, Richard Vogel, Troy Seidle, Horst Spielmann

Troy Seidle, PhD

The European Union’s Registration, Evaluation and Authorisation of Chemicals (REACH) legislation mandates testing and evaluation of approximately 30,000 existing substances within a short period of time, beginning with the most widely used “high production volume” (HPV) chemicals. REACH testing requirements for the roughly 3000 HPV chemicals specify three separate tests for reproductive toxicity: two developmental toxicity studies on different animal species (OECD Test Guideline 414) and a two-generation reproduction toxicity study (OECD TG 416). These studies are highly costly in both economic and animal welfare terms. OECD TG 416 is a fertility study intended to evaluate reproductive performance of animals …


Cetaceans And Marine Debris: The Great Unknown, Mark Peter Simmonds Dec 2014

Cetaceans And Marine Debris: The Great Unknown, Mark Peter Simmonds

Mark P. Simmonds, OBE

Plastics and other marine debris have been found in the gastrointestinal tracts of cetaceans, including instances where large quantities of material have been found that are likely to cause impairment to digestive processes and other examples, where other morbidity and even death have resulted. In some instances, debris may have been ingested as a result of the stranding process and, in others, it may have been ingested when feeding. Those species that are suction or “ram” feeders may be most at risk. There is also evidence of entanglement of cetaceans in marine debris. However, it is usually difficult to distinguish …


The Public Health Impacts Of Concentrated Animal Feeding Operations On Local Communities, Michael Greger, Gowri Koneswaran May 2014

The Public Health Impacts Of Concentrated Animal Feeding Operations On Local Communities, Michael Greger, Gowri Koneswaran

Michael Greger, MD, FACLM

Large-scale farm animal production facilities, also known as concentrated animal feeding operations (CAFOs), release a significant amount of contaminants into the air and water. Adverse health effects related to exposure to these contaminants among CAFO workers have been welldocumented; however, less is known about their impact on the health of residents in nearby communities. Epidemiological research in this area suggests that neighboring residents are at increased risk of developing neurobehavioral symptoms and respiratory illnesses, including asthma. Additional research is needed to better understand community-scale exposures and health outcomes related to the management practices and emissions of CAFOs.


Susceptibility Of Quagga Mussels (Dreissena Rostriformis Bugensis) To Hot-Water Sprays As A Means Of Watercraft Decontamination, Sean Comeau, Scott Rainville, Wen Baldwin, Emily Austin, Shawn Gerstenberger, Chad Cross, Wai Wong Mar 2014

Susceptibility Of Quagga Mussels (Dreissena Rostriformis Bugensis) To Hot-Water Sprays As A Means Of Watercraft Decontamination, Sean Comeau, Scott Rainville, Wen Baldwin, Emily Austin, Shawn Gerstenberger, Chad Cross, Wai Wong

Shawn Gerstenberger

The recent spread of dreissenid mussels to various bodies of water in the western US has sparked interest by many state and federal agencies to develop protocols to stop further expansion. Quagga mussels (Dreissena rostriformis bugensis) are of particular importance as they are currently the most widespread dreissenid species in the region. This project examined the susceptibility of quagga mussels to hot-water sprays at different temperatures and durations of spray contact at Lake Mead (Nevada-Arizona, USA). Emersed adult quagga mussels were exposed to hot-water sprays at 20, 40, 50, 54, 60, 70, and 80°C for 1, 2, 5, 10, 20, …


Estimating Survival Rates Of Quagga Mussel (Dreissena Rostriformis Bugensis) Veliger Larvae Under Summer And Autumn Temperature Regimes In Residual Water Of Trailered Watercraft At Lake Mead, Usa, W. Choi, Shawn Gerstenberger, R. Mcmahon, Wai Wong Mar 2014

Estimating Survival Rates Of Quagga Mussel (Dreissena Rostriformis Bugensis) Veliger Larvae Under Summer And Autumn Temperature Regimes In Residual Water Of Trailered Watercraft At Lake Mead, Usa, W. Choi, Shawn Gerstenberger, R. Mcmahon, Wai Wong

Shawn Gerstenberger

No abstract provided.


An Evaluation Of Mercury Concentrations In Three Brands Of Canned Tuna, Shawn Gerstenberger, Adam Martinson, Joanna Kramer Mar 2014

An Evaluation Of Mercury Concentrations In Three Brands Of Canned Tuna, Shawn Gerstenberger, Adam Martinson, Joanna Kramer

Shawn Gerstenberger

There is widespread concern over the presence of Hg in fish consumed by humans. While studies have been focused on determining the Hg concentration in sport fish and some commercial fish, little attention has been directed to canned tuna; it is widely held that concentrations are low. In the present study, the amount of Hg present in canned tuna purchased in Las Vegas, Nevada, USA, was examined, and the brand, temporal variation, type, and packaging medium impacts on Hg concentrations in tuna were explored. A significant (p < 0.001) brand difference was noted: Brand 3 contained higher Hg concentrations ($\bar x$ …


Microbes In Pool Filter Backwash As Evidence Of The Need For Improved Swimmer Hygiene — Metro-Atlanta, Georgia, 2012, Christopher Hutcheson, Ryan Cira, Stanley L. Gaines, Kevin R. Jones, Walter Howard, David Hornsby, Maurice Redmond, R. Christopher Rustin, Michele C. Hlavsa, Jennifer L. Murphy, Jothikumar Narayanan, Candace D. Miller, Brittany Cantrell, Vincent R. Hill, Michael J. Beach May 2013

Microbes In Pool Filter Backwash As Evidence Of The Need For Improved Swimmer Hygiene — Metro-Atlanta, Georgia, 2012, Christopher Hutcheson, Ryan Cira, Stanley L. Gaines, Kevin R. Jones, Walter Howard, David Hornsby, Maurice Redmond, R. Christopher Rustin, Michele C. Hlavsa, Jennifer L. Murphy, Jothikumar Narayanan, Candace D. Miller, Brittany Cantrell, Vincent R. Hill, Michael J. Beach

R. Christopher Rustin

Abstract not available.


The “Green Eating” Project: A Pilot Intervention To Promote Sustainable And Healthy Eating In College Students, Kelleigh E. Eastman Apr 2013

The “Green Eating” Project: A Pilot Intervention To Promote Sustainable And Healthy Eating In College Students, Kelleigh E. Eastman

Geoffrey Greene

The “Green Eating” Project: A Pilot Intervention to Promote Sustainable and Healthy Eating in College Students Kelleigh Eastman Sponsor: Geoffrey Greene, Nutrition and Dietetics A topic of interest that is growing in the general population is the idea of being sustainable, or “green”, and there is a rising awareness in sustainable practices involving food and the environment. Some of the “green” eating behaviors identified through my research included eating a plant-based (i.e. vegetarian or semi-vegetarian) diet, eating locally grown foods, eating organically grown foods, and eating foods that are labeled fair-trade. Frequently, these “green” eating behaviors are healthful eating behaviors …


Predicting Modes Of Toxic Action From Chemical Structure, Steven P. Bradbury, Christine L. Russom, Steven J. Broderius, Dean J. Hammermeister, Robert A. Drummond, Gilman D. Veith Jan 2013

Predicting Modes Of Toxic Action From Chemical Structure, Steven P. Bradbury, Christine L. Russom, Steven J. Broderius, Dean J. Hammermeister, Robert A. Drummond, Gilman D. Veith

Steven P. Bradbury

Like many of the papers in the Environmental Toxicology and Chemistry “Top 100” list, the development of the fathead minnow database [1] and the assignment of modes of action to the 617 chemicals therein resulted from a comprehensive research effort by a multidisciplinary team of researchers with expertise in quantitative structure–activity relationship (QSAR) modeling, chemistry, toxicokinetics, joint toxicity of chemical mixtures, and behavioral and aquatic toxicology. The fathead minnow database was the culmination of the US Environmental Protection Agency’s (USEPA) QSAR research program, which spanned nearly 20 yr, a rare program because many research planning efforts typically run within a …


The Usage Of Natural Fertilizers - A Practice That Favors The Ecological Agriculture Development In Romania, Andreea Ghiurcă, Andreea Lămășanu, Florin C. Mihai Apr 2012

The Usage Of Natural Fertilizers - A Practice That Favors The Ecological Agriculture Development In Romania, Andreea Ghiurcă, Andreea Lămășanu, Florin C. Mihai

Florin C MIHAI

Natural fertilizers were used in agriculture since ancient times and are still the best method of soil fertilization. Traditional agriculture, practiced in rural areas of Romania, contributes to the maintenance of soils fertilization ecological practices. Our research shows the evolution of the quantity of natural fertilizers used in the past 20 years at the national level and at the level of NeamŃ County captures the evolution over the seven years of natural fertilizers areas. In the analyzed period, the quantity of natural fertilizers on agricultural land is growing, but fertilized land record low values, showing that it has increased the …


Food Benefit And Climate Warming Potential Of Nitrogen Fertilizer Uses In China, Hanqin Tian, Chaoqun (Crystal) Lu, Jerry Melillo, Wei Ren, Yao Huang, Xiaofeng Xu, Mingliang Liu, Chi Zhang, Guangsheng Chen, Shufen Pan, Jiyuan Liu, John Reilly Jan 2012

Food Benefit And Climate Warming Potential Of Nitrogen Fertilizer Uses In China, Hanqin Tian, Chaoqun (Crystal) Lu, Jerry Melillo, Wei Ren, Yao Huang, Xiaofeng Xu, Mingliang Liu, Chi Zhang, Guangsheng Chen, Shufen Pan, Jiyuan Liu, John Reilly

Chaoqun (Crystal) Lu

Chemical nitrogen (N) fertilizer has long been used to help meet the increasing food demands in China, the top N fertilizer consumer in the world. Growing concerns have been raised on the impacts of N fertilizer uses on food security and climate change, which is lack of quantification. Here we use a carbon–nitrogen (C–N) coupled ecosystem model, to quantify the food benefit and climate consequence of agronomic N addition in China over the six decades from 1949 to 2008. Results show that N fertilizer-induced crop yield and soil C sequestration had reached their peaks, while nitrous oxide (N2O) emission continued …


High Speed Flight At Low Altitude: Hazard To Commercial Aviation ?, Paul F. Eschenfelder , Capt. Mar 2011

High Speed Flight At Low Altitude: Hazard To Commercial Aviation ?, Paul F. Eschenfelder , Capt.

Paul F. Eschenfelder

Commercial aircraft are capable of, and in fact, do, operate at high speed (>250 knots indicated airspeed [KIAS]) at low altitude (below 10,000’ above ground level) worldwide. Design, construction and certification standards for these aircraft were developed over 40 years ago. Since the development of these standards populations of large flocking birds have increased dramatically in many parts of the world. Yet neither design/construction standards nor operational practice have changed to reflect the new threat. Subsequent serious damage resulting from recent collisions indicates change is necessary. Since 2003, flight rules in Canada and the United States have been amended, …


Integrating Avian Radar Into The Aviation Operating Environment, Richard Sowden, Paul Eschenfelder Mar 2011

Integrating Avian Radar Into The Aviation Operating Environment, Richard Sowden, Paul Eschenfelder

Paul F. Eschenfelder

Avian radar technology has matured to the point where robust data and analysis tools are now able to provide the aviation industry with high quality information to support bird strike risk mitigation activities. The aviation operating environment is dynamic and challenging with complex interactions between the primary bird strike risk mitigation stakeholders; airport operators, air traffic service providers and flight crews. The transfer of this proof of concept technology into a suite of tools that is integrated into the aviation industry requires the engagement and support of the user community in the next critical evolutionary step of this emerging technology. …


Eschar-Associated Spotted Fever Rickettsiosis, Bahia, Brazil, Nanci Silva, Marina Eremeeva, Tatiana Rozental, Guilherme S. Ribeiro, Christopher D. Paddock, Eduardo Antonio G. Ramos, Alexsandra R.M. Favacho, Mitermayer G. Reis, Gregory A. Dasch,, Elba R.S. De Lemos, Albert I. Ko Feb 2011

Eschar-Associated Spotted Fever Rickettsiosis, Bahia, Brazil, Nanci Silva, Marina Eremeeva, Tatiana Rozental, Guilherme S. Ribeiro, Christopher D. Paddock, Eduardo Antonio G. Ramos, Alexsandra R.M. Favacho, Mitermayer G. Reis, Gregory A. Dasch,, Elba R.S. De Lemos, Albert I. Ko

Marina E. Eremeeva

In Brazil, Brazilian spotted fever was once considered the only tick-borne rickettsial disease. We report eschar-associated rickettsial disease that occurred after a tick bite. The etiologic agent is most related to Rickettsia parkeri, R. africae, and R. sibirica and probably widely distributed from São Paulo to Bahia in the Atlantic Forest.


Emergence Of A Novel Human Ehrlichia-Muris Like Organism In North America – Wisconsin And Minnesota, Bobbi S. Pritt, Lynne M. Sloan, Diep K. Hoang-Johnson, Ulrike G. Munderloh, Susan M. Paskewitz, Kristina M. Mcelroy, Jevon D. Mcfadden, Matthew J. Binnicker, David F. Neitzel, Gongping Liu, William L. Nicholson, Curtis M. Nelson, Joni J. Franson, Scott A. Martin, Scott A. Cunningham, Christopher R. Steward, Kay Bogumill, Mary E. Bjorgaard, Jeffrey P. Davis, Jennifer H. Mcquiston, David M. Warshauer, Mark P. Wilhelm, Robin Patel, Vipul A. Trivedi, Marina Eremeeva Jan 2011

Emergence Of A Novel Human Ehrlichia-Muris Like Organism In North America – Wisconsin And Minnesota, Bobbi S. Pritt, Lynne M. Sloan, Diep K. Hoang-Johnson, Ulrike G. Munderloh, Susan M. Paskewitz, Kristina M. Mcelroy, Jevon D. Mcfadden, Matthew J. Binnicker, David F. Neitzel, Gongping Liu, William L. Nicholson, Curtis M. Nelson, Joni J. Franson, Scott A. Martin, Scott A. Cunningham, Christopher R. Steward, Kay Bogumill, Mary E. Bjorgaard, Jeffrey P. Davis, Jennifer H. Mcquiston, David M. Warshauer, Mark P. Wilhelm, Robin Patel, Vipul A. Trivedi, Marina Eremeeva

Marina E. Eremeeva

Background: Ehrlichiosis is a clinically important, emerging zoonosis. Only Ehrlichia chaffeensis and E. ewingii have been thought to cause ehrlichiosis in humans in the United States. Patients with suspected ehrlichiosis routinely undergo testing to ensure proper diagnosis and to ascertain the cause.

Methods: We used molecular methods, culturing, and serologic testing to diagnose and ascertain the cause of cases of ehrlichiosis.

Results: On testing, four cases of ehrlichiosis in Minnesota or Wisconsin were found not to be from E. chaffeensis or E. ewingii and instead to be caused by a newly discovered ehrlichia species.

All patients had fever, …


Rocky Mountain Spotted Fever In Panama: A Cluster Description, Maribel Tribaldos, Yamitzel Zaldivar, Sergio Bermudez, Franklyn Samudio, Yaxelis Mendoza, Alexander A. Martinez, Rodrigo Villalobos, Marina Eremeeva, Christopher D. Paddock, Kathleen Page, Rebecca E. Smith, Juan Miguel Pascale Jan 2011

Rocky Mountain Spotted Fever In Panama: A Cluster Description, Maribel Tribaldos, Yamitzel Zaldivar, Sergio Bermudez, Franklyn Samudio, Yaxelis Mendoza, Alexander A. Martinez, Rodrigo Villalobos, Marina Eremeeva, Christopher D. Paddock, Kathleen Page, Rebecca E. Smith, Juan Miguel Pascale

Marina E. Eremeeva

Rocky Mountain spotted fever (RMSF) is a tick-borne infection caused by Rickettsia rickettsii. We report a cluster of fatal cases of RMSF in 2007 in Panama, involving a pregnant woman and two children from the same family. The woman presented with a fever followed by respiratory distress, maculopapular rash, and an eschar at the site from which a tick had been removed. She died four days after disease onset. This is the second published report of an eschar in a patient confirmed by PCR to be infected with R. rickettsii. One month later, the children presented within days of one …


Aflatoxin B1 Albumin Adducts In Plasma And Aflatoxin M1 In Urine Are Associated With Plasma Concentrations Of Vitamins A And E, Francis A. Obuseh, Pauline E. Jolly, Yi Jiang, Faisal M. B. Shuaib, John Waterbor, William O. Ellis, Chandrika J. Piyathilake, Renee A. Desmond, Evans Afriyie-Gyawu, Timothy D. Phillips Dec 2010

Aflatoxin B1 Albumin Adducts In Plasma And Aflatoxin M1 In Urine Are Associated With Plasma Concentrations Of Vitamins A And E, Francis A. Obuseh, Pauline E. Jolly, Yi Jiang, Faisal M. B. Shuaib, John Waterbor, William O. Ellis, Chandrika J. Piyathilake, Renee A. Desmond, Evans Afriyie-Gyawu, Timothy D. Phillips

Evans Afriyie-Gyawu

Background: Although aflatoxin exposure has been shown to be associated with micronutrient deficiency in animals, there are few investigations on the effects of aflatoxin exposure on micronutrient metabolism in humans.
Objective: To examine the relationship between aflatoxin B1 (AFB1) albumin adducts (AF-ALB) in plasma and the aflatoxin M1 (AFM1) metabolite in urine and plasma concentrations of retinol (vitamin A) and α-tocopherol (vitamin E) in Ghanaians.
Methods: A cross-sectional study of 147 adult participants was conducted. Blood and urine samples were tested for aflatoxin and vitamins A and E levels.
Results: Multivariable analysis showed that participants with high AF-ALB (≥ 0.80 …


Qsar Prioritization Of Chemical Inventories For Endocrine Disruptor Testing, Steven P. Bradbury, Patricia Schmeider, Ovanes Mekenyan, Gilman Veith Jan 2003

Qsar Prioritization Of Chemical Inventories For Endocrine Disruptor Testing, Steven P. Bradbury, Patricia Schmeider, Ovanes Mekenyan, Gilman Veith

Steven P. Bradbury

Binding affinity between chemicals and the estrogen receptor (ER) serves as an indicator of the potential to cause endocrine disruption through this receptor-mediated endocrine pathway. Estimating ER-binding affinity is, therefore, one strategic approach to reducing the costs of screening chemicals for potential risks of endocrine disruption. While measuring ER binding with in vitro assays may be the first choice in prioritizing chemicals for additional in vitro or in vivo estrogenicity testing, the time and costs associated with screening thousands of chemicals is prohibitive. Recent advances in 3D modeling of the reactivity of flexible structures make in silico methods for estimating …


Influence Of Suspended Solids On Acute Toxicity Of Carbofuran To Daphnia Magna: I. Interactive Effects, Steven P. Bradbury, Carl Herbrandson, Deborah L. Swackhamer Jan 2003

Influence Of Suspended Solids On Acute Toxicity Of Carbofuran To Daphnia Magna: I. Interactive Effects, Steven P. Bradbury, Carl Herbrandson, Deborah L. Swackhamer

Steven P. Bradbury

This study explored the effects on Daphnia magna from exposure to the pesticide carbofuran in combination with stress from suspended solids exposure. Our objective was to assess whether suspended solids affects the toxicodynamic response of D. magna to carbofuran. A series of laboratory experiments was performed where animals were exposed to carbofuran concentrations ranging from 0 to 160 mg/l in combination with suspended solids concentrations ranging from 0 to 10,000 mg/l. In the absence of suspended solids, effects of carbofuran were dose dependent and resulted in an EC(sub)50 of 92 mg/l. Exposure to suspended solids, up to extreme levels that …


Derivation Of Wildlife Values For Mercury, Steven P. Bradbury, John Nichols, Jeff Swartout Jan 1999

Derivation Of Wildlife Values For Mercury, Steven P. Bradbury, John Nichols, Jeff Swartout

Steven P. Bradbury

A procedure has been developed to estimate surface water concentrations of toxicants (“wildlife values”) that will protect the viability of wildlife populations associated with aquatic resources. This procedure was designed primarily to protect piscivorous birds and mammals from compounds that bioaccumulate in fish and was used in the Great Lakes Water Quality Initiative (GLI) to calculate wildlife values (WV) for mercury, DDT/DDE, total polychlorinated biphenyls (PCBs), and 2,3,7,8-tetrachlorodibenzodioxin (TCDD). Published in 1995, and expressed as total mercury in unfiltered water, the final wildlife value (WVf) for mercury derived in the GLI was 1300 pg Hg/L. This value was selected as …


Removal Of Phosphorus From Static Sewage Effluent By Waterhyacinth, W Harold Ornes Dec 1974

Removal Of Phosphorus From Static Sewage Effluent By Waterhyacinth, W Harold Ornes

W. Harold Ornes

Waterhyacinth [Eichhornia crassipes (Mart.) Solms] was grown in static sewage effluent during May to July 1974 in outdoor concrete containers with a capacity of 760 liters and a surface area of 1.66 m². The plants were removed weekly from one-half of the surface area of the containers during 5-wk growth periods. Tissue phosphorus (P) and nitrogen (N), plant productivity, and some parameters of water quality were measured. A maximum uptake of 5,500 µg of P/g dry weight of plant material occurred when the level of orthophosphate phosphorus (available P) in the effluent was 1.1 µg/ml. Phosphorus in the effluent was …