Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Life Sciences
A Determining Factor For Insect Feeding Preference In The Silkworm, Bombyx Mori, Zhong-Jie Zhang, Shuai-Shuai Zhang, Bao-Long Niu, Dong-Feng Ji, Xiao-Jing Liu, Mu-Wang Li, Hua Bai, Subba Reddy Palli, Chen-Zhu Wang, An-Jiang Tan
A Determining Factor For Insect Feeding Preference In The Silkworm, Bombyx Mori, Zhong-Jie Zhang, Shuai-Shuai Zhang, Bao-Long Niu, Dong-Feng Ji, Xiao-Jing Liu, Mu-Wang Li, Hua Bai, Subba Reddy Palli, Chen-Zhu Wang, An-Jiang Tan
Entomology Faculty Publications
Feeding preference is critical for insect adaptation and survival. However, little is known regarding the determination of insect feeding preference, and the genetic basis is poorly understood. As a model lepidopteran insect with economic importance, the domesticated silkworm, Bombyx mori, is a well-known monophagous insect that predominantly feeds on fresh mulberry leaves. This species-specific feeding preference provides an excellent model for investigation of host-plant selection of insects, although the molecular mechanism underlying this phenomenon remains unknown. Here, we describe the gene GR66, which encodes a putative bitter gustatory receptor (GR) that is responsible for the mulberry-specific feeding preference …
The Foxo Transcription Factor Controls Insect Growth And Development By Regulating Juvenile Hormone Degradation In The Silkworm, Bombyx Mori, Baosheng Zeng, Yuping Huang, Jun Xu, Takahiro Shiotsuki, Hua Bai, Subba Reddy Palli, Yongping Huang, Anjiang Tan
The Foxo Transcription Factor Controls Insect Growth And Development By Regulating Juvenile Hormone Degradation In The Silkworm, Bombyx Mori, Baosheng Zeng, Yuping Huang, Jun Xu, Takahiro Shiotsuki, Hua Bai, Subba Reddy Palli, Yongping Huang, Anjiang Tan
Entomology Faculty Publications
Forkhead box O (FOXO) functions as the terminal transcription factor of the insulin signaling pathway and regulates multiple physiological processes in many organisms, including lifespan in insects. However, how FOXO interacts with hormone signaling to modulate insect growth and development is largely unknown. Here, using the transgene-based CRISPR/Cas9 system, we generated and characterized mutants of the silkworm Bombyx mori FOXO (BmFOXO) to elucidate its physiological functions during development of this lepidopteran insect. The BmFOXO mutant (FOXO-M) exhibited growth delays from the first larval stage and showed precocious metamorphosis, pupating at the end of the fourth instar (trimolter) rather …