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Full-Text Articles in Life Sciences
Juvenile Hormone And Insulin Regulate Trehalose Homeostasis In The Red Flour Beetle, Tribolium Castaneum, Jingjing Xu, Zhentao Sheng, Subba R. Palli
Juvenile Hormone And Insulin Regulate Trehalose Homeostasis In The Red Flour Beetle, Tribolium Castaneum, Jingjing Xu, Zhentao Sheng, Subba R. Palli
Entomology Faculty Publications
Insulin/IGF-1 signaling (IIS) has been well studied for its role in the control of life span extension and resistance to a variety of stresses. The Drosophila melanogaster insulin-like receptor (InR) mutant showed extended life span due to reduced juvenile hormone (JH) levels. However, little is known about the mechanism of cross talk between IIS and JH in regulation of life span extension and resistance to starvation. In the current study, we investigated the role of IIS and JH signaling in regulation of resistance to starvation. Reduction in JH biosynthesis, JH action, or insulin-like peptide 2 (ILP2) syntheses by RNA interference …