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Articles 1 - 9 of 9
Full-Text Articles in Life Sciences
The Kinetics Of Biocontaminant Inactivation: A Comparative Study With Bacillus Globigii And Bacillus Anthracis, Leigh M. Durden
The Kinetics Of Biocontaminant Inactivation: A Comparative Study With Bacillus Globigii And Bacillus Anthracis, Leigh M. Durden
Theses and Dissertations
Bacillus anthracis has been a biological threat for decades and after the 2001 terrorist attack via the U.S. Postal Service where five people died, there was heightened awareness and inquiry on the subject (Goel, 2015; Greenberg et al., 2010; Nicholson & Galeano, 2003; Spotts Whitney et al., 2003). The health risk to humans makes this biological agent, a Tier 1 agent and one of the most likely to be used in an attack (Anthrax as a Bioterrorism Weapon | CDC, n.d.; Driks, 2009; Rose & Rice, 2014). B. anthracis is one of most resistant and potent biological warfare agents as …
Human Optimization And Performance Enhancement In Flight Via Real-Time Biofeedback (Project Have Hope), Michael S. Fritts
Human Optimization And Performance Enhancement In Flight Via Real-Time Biofeedback (Project Have Hope), Michael S. Fritts
Theses and Dissertations
A four-phase, chronological, and build-up approach was implemented that commenced with basic hardware testing in a centrifuge and culminated in flights augmented by real-time biofeedback displays. A prototype Portable Electrocardiogram Unit (PECGU) was designed and proven to accurately measure heart rate (HR) and display percent heart rate reserve (%HRR). Results showed that %HRR was not a sole predictor of cognitive state. Cognitive responses indicated some correlation with %HRR, but were influenced by environment (centrifuge vs. flight). Subjective perceived exertion levels did not show statistically significant changes during test with biofeedback. A G-tracking task was evaluated during centrifuge and flight tests. …
Analysis Of Bacterial Population And Distribution In The Developing Strata Of A Constructed Wetland Used For Chlorinated Ethene Bioremediation, Milton J. Clausen Jr.
Analysis Of Bacterial Population And Distribution In The Developing Strata Of A Constructed Wetland Used For Chlorinated Ethene Bioremediation, Milton J. Clausen Jr.
Theses and Dissertations
Chlorinated hydrocarbons and their degradation products are among of the most common organic groundwater contaminates in the United States. These compounds attack the central nervous system in animals and can affect the photosynthesis of plants. These compounds are also resistant to degradation in the environment and, because of this, pose a risk to any ecosystem in which they are present. This study identified the dominant microbial species in a constructed treatment wetland at Wright-Patterson AFB, Dayton, Ohio using 16S rRNA gene sequence analysis. Samples were taken from three different depths and during each of the four seasons. These samples were …
In Vitro Toxicity Of Aluminum Nanoparticles In Rat Alveolar Macrophages, Andrew J. Wagner
In Vitro Toxicity Of Aluminum Nanoparticles In Rat Alveolar Macrophages, Andrew J. Wagner
Theses and Dissertations
Nanomaterials, which are by definition in the 1 - 100 nanometer range, have numerous possible benefits to society, but currently there is a lack of data that characterizes these materials effects on human health and environment. In general nanomaterials are of interest to the Air Force because of their applications in electronics, sensors, munitions and energetic/reactive systems. Nanoparticles such as aluminum have been considered for enhancing propulsion in solid rocket fuel. To date, only a few studies have looked at the toxicological effects of direct exposure to nanoparticles, none with aluminum. It is important to increase the understanding of the …
An Analysis Of Microbial Contamination In Military Aviation Fuel Systems, Harold W. Graef
An Analysis Of Microbial Contamination In Military Aviation Fuel Systems, Harold W. Graef
Theses and Dissertations
Military aviation fuel systems can be an ideal environment for microorganisms. Microbial growth in hydrocarbon fuel systems arises because of the impracticality of keeping fuel tanks sterile and the inevitable presence of water from condensation. Microbial contaminants in aviation fuel systems are a concern because of their potential to degrade the fuel, accelerate tank corrosion, and threaten flight safety. This research addresses the concern of using more environmentally friendly Fuel System Icing Inhibitors (FSII), which are also biocidal. Are significant levels of microorganisms growing in military aviation fuel systems, and if so, are there any common variables? Forty aviation fuel …
Pilot Mental Workload Calibration, Jeremy B. Noel
Pilot Mental Workload Calibration, Jeremy B. Noel
Theses and Dissertations
Predicting high pilot mental workload is important to the U.S. Air Force because lives and aircraft can be lost when errors are made during periods of mental overload and task saturation. Current research efforts use psychophysiological measures such as electroencephalography, cardiac, ocular, and respiration measures in an attempt to identify and predict mental workload levels. The primary focus of this effort is the development of a calibration scheme that allows a small subset of salient psychophysiological features developed using actual flight data for one pilot on a given day to accurately classify pilot mental workload for a separate pilot on …
Metabolic Inhibition Of A Toluene-Enriched Microbial Population Due To Lead (Pb2+): Verification Of A Free Metal Ion Toxicity Model, Patrick J. S. Marbas
Metabolic Inhibition Of A Toluene-Enriched Microbial Population Due To Lead (Pb2+): Verification Of A Free Metal Ion Toxicity Model, Patrick J. S. Marbas
Theses and Dissertations
A dissolved oxygen probe and an ion specific electrode were used to study the lead-induced metabolic inhibition in a toluene-enriched microbial population. Predicted toxicity values were compared to the actual toxicity responses using a free metal ion toxicity model (TM) which linked metabolic inhibition with lead activity. Experimentally derived values for the model parameters (lead activity and a lead distribution coefficient) were used in the TM. It was postulated that cellular metabolism is disrupted by the conformational changes to the cell's plasma membrane produced by lead ion adsorption. The predicted toxicity values were higher than the actual toxicity response. This …
A Risk Assessment Of The Health Liabilities From Exposure To Toxic Metals Found In The Composted Material Of Air Force Municipal Solid Waste, Timothy L. Merrymon
A Risk Assessment Of The Health Liabilities From Exposure To Toxic Metals Found In The Composted Material Of Air Force Municipal Solid Waste, Timothy L. Merrymon
Theses and Dissertations
This thesis assesses the risk of the health liabilities from exposure to toxic metals found in the composted material of Air Force municipal solid waste (MSW). The goal is to determine the probability that the composted MSW could be a health hazard if it were used as a soil amendment. The research limited the assessment of the exposure risk to heavy metals found in raw MSW and its resulting compost. The thesis uses reviews of present literature to examine the food and soil ingestion exposure pathways. These pathways are assessed using the heavy metal concentrations found in MSW compost and …
A Refinement Of Risk Analysis Procedures For Trichloroethylene Through The Use Of Monte Carlo Method In Conjunction With Physiologically Based Pharmacokinetic Modeling, William J. Cronin Iv, Eric J. Oswald
A Refinement Of Risk Analysis Procedures For Trichloroethylene Through The Use Of Monte Carlo Method In Conjunction With Physiologically Based Pharmacokinetic Modeling, William J. Cronin Iv, Eric J. Oswald
Theses and Dissertations
This study refines risk analysis procedures for trichloroethylene (TCE) using a physiologically based pharmacokinetic (PBPK) model in conjunction with the Monte Carlo method. The Monte Carlo method is used to generate random sets of model parameters, based on the mean, variance, and distribution types. The procedure generates a range of exposure values for human excess lifetime cancer risk of lxl0 (exp-6), based on the upper and lower bounds and the mean of a 95% confidence interval. Risk ranges were produced for both ingestion and inhalation exposures. Results are presented in a graphical format to reduce reliance on qualitative discussions of …