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Full-Text Articles in Life Sciences

Seasonal Variation In Home-Range And Core-Area Size In Verreaux's Sifaka, Brynn Harshbarger Jan 2021

Seasonal Variation In Home-Range And Core-Area Size In Verreaux's Sifaka, Brynn Harshbarger

Theses, Dissertations and Capstones

Primates living in seasonal forests must adapt to extreme fluctuation in resource availability. Verreaux’s sifaka ( ) live in Madagascar’s highly seasonal tropical dry forests and experience periods of extreme resource abundance and scarcity. Home- range and core-area size were measured using 95% and 50% kernel estimation, and 95% minimum convex polygons to compare seasonal shifts in space use based on resource availability. There have been no long-term space use studies on Verreaux’s sifaka; therefore, we do not know how their space use changes over time in an environment which is both highly seasonal and highly variable. Our study leverages …


Crippling Rapid Evolution Of Metastasis And Drug Resistance In A549 Non-Small Cell Lung Cancer Cells With The Clinically Relevant Hsp90 Inhibitor Auy922, Nickolas Anthony Bacon Jan 2021

Crippling Rapid Evolution Of Metastasis And Drug Resistance In A549 Non-Small Cell Lung Cancer Cells With The Clinically Relevant Hsp90 Inhibitor Auy922, Nickolas Anthony Bacon

Theses, Dissertations and Capstones

The ability for species to evolve new features in response to changing circumstances in order to survive and propagate is a ubiquitous observation on both the macroscopic and microscopic levels of living systems. It should be no surprise, then, that diseases such as cancer utilize their own forms of adaptation to perpetuate themselves when exposed to external threats. Indeed, concepts drawn from Darwinian evolution are now widely accepted to help explain certain aspects of carcinogenesis and malignant progression, the sum of which have come to be known as the theory of tumor evolution. Since metastasis and drug resistance are features …


Assessing The Toxicity Of A Reconstituted Water Simulating Streams Influenced By Mountaintop Mining In Central Appalachia, Benjamin David Browning Jan 2021

Assessing The Toxicity Of A Reconstituted Water Simulating Streams Influenced By Mountaintop Mining In Central Appalachia, Benjamin David Browning

Theses, Dissertations and Capstones

Freshwater ecosystems in Central Appalachia experience increased concentrations of manganese (Mn) and total dissolved solids from the runoff of surface mines and valley fills. Biological communities have been impacted by these surface mining operations and it has been suggested that the increase in total dissolved solids may contribute to these negative effects, but standard laboratory toxicity tests have not found increased concentrations of total dissolved solids to have such negative effects as seen in the field. The elevated total dissolved solids in mining influenced streams may only be toxic in conjunction with another toxicant that is presence in these systems …


The Effects Of Fire On Oak-Forest Plant Communities Along Soil Moisture Gradients: A 25-Year Study, Rebekah Frances Shupe Jan 2021

The Effects Of Fire On Oak-Forest Plant Communities Along Soil Moisture Gradients: A 25-Year Study, Rebekah Frances Shupe

Theses, Dissertations and Capstones

In the eastern U.S., fire is a natural disturbance process in Quercus (oak) forests. Fire is thought to promote oak regeneration and plant diversity by reducing competition, preparing a suitable seedbed, and increasing light availability. However, the era of fire suppression that began in the early 20th century is thought to have negatively impacted oak regeneration and the biodiversity of the understory layer. In this study, we examined the effects of prescribed fire on tree regeneration and the understory layer over 25 years. From a study initiated in 1994, we resampled 45 permanent vegetation plots measuring 1250 m2 …


An Exceptionally Small New Polycotylid Plesiosaur (Reptilia: Sauropterygia) With Raptorial Eyes From The Western Interior Seaway Of North America, Robert O’Brien Clark Jan 2021

An Exceptionally Small New Polycotylid Plesiosaur (Reptilia: Sauropterygia) With Raptorial Eyes From The Western Interior Seaway Of North America, Robert O’Brien Clark

Theses, Dissertations and Capstones

Polycotylidae is a family of plesiosaurian marine reptiles that evolved during the Early Cretaceous and radiated into multiple genera during the Late Cretaceous, achieving a worldwide distribution. Derived polycotylids of the subclade Polycotylinae have a gracile and elongated rostrum, homodont dentition, an extended mandibular symphysis, and foreshortened temporal fenestrae. In this thesis, I describe a small and highly derived new polycotylid taxon based on three specimens from the Campanian of the Western Interior Seaway in North America. A high number of maxillary teeth, fused neural arches, propodials with well-defined facets, and heavily remodeled cortical bone indicate the specimens are adults, …