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- 10.7454/mss.v27i4.1349 (1)
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Articles 1 - 9 of 9
Full-Text Articles in Life Sciences
Free-Radical Scavenging Activity And Total Phenolic Compounds Of Red And Green Poinsettia Leaves (Euphorbia Pulcherrima Willd.) From Lombok Island, Handa Muliasari, Baiq Sopiah, Emmy Yuanita, Baiq Nila Sari Ningsih
Free-Radical Scavenging Activity And Total Phenolic Compounds Of Red And Green Poinsettia Leaves (Euphorbia Pulcherrima Willd.) From Lombok Island, Handa Muliasari, Baiq Sopiah, Emmy Yuanita, Baiq Nila Sari Ningsih
Makara Journal of Science
To determine the free-radical scavenging activity and total phenolic content of the ethanol extract of Poinsettia leaves (Euphorbia pulcherrima Willd.) from Lombok Island, we used the 1,1-diphenyl-2-picrylhydrazyl method and expressed the total phenolic content as gallic acid equivalent (GAE) per gram of ethanol extract. The results show the strong antioxidant activity (79.77 ppm) of the ethanol extract of red Poinsettia leaves and the moderate antioxidant activity of green Poinsettia leaves (118.350 ppm). The ethanol extracts of red and green Poinsettia leaves possessed an average of 63.276 ± 0.228 and 22.715 ± 0.090 mg GAE/g extract total phenolic contents, respectively. …
Enzymatic Screening And Genotypic Characterization Of Thermophilic Bacteria From The Hot Springs Of Sarawak, Malaysia, Seng Chiew Toh, Samuel Lihan, Sui Sien Leong, Azizul Hakim Lahuri, Wai Cheong Woon, Wing Woh Ng
Enzymatic Screening And Genotypic Characterization Of Thermophilic Bacteria From The Hot Springs Of Sarawak, Malaysia, Seng Chiew Toh, Samuel Lihan, Sui Sien Leong, Azizul Hakim Lahuri, Wai Cheong Woon, Wing Woh Ng
Makara Journal of Science
Owing to their eccentric thermostable ability, thermophiles are among the most utilized extremophiles in various industries, such as manufacturing, and clinical research. Researchers believe that many unknown thermophiles are yet to be discovered. This study aimed to genotypically characterize the diversity of thermophiles and screen them for the potential production of enzymes in the recreational hot springs located at Northwest Coast of Borneo. Water samples were collected at 45 °C–50 °C from Annah Rais and Panchor hot springs during the sampling period from January 2018 to January 2019. Three samples (water and sediment) were collected twice in a 3-week interval …
Isolation Of Lignin From Sugarcane Bagasse As An Adsorbent For Chromium Ion, Nila Tanyela Berghuis, Nurul Fitri Novianti, Paramita Jaya Ratri
Isolation Of Lignin From Sugarcane Bagasse As An Adsorbent For Chromium Ion, Nila Tanyela Berghuis, Nurul Fitri Novianti, Paramita Jaya Ratri
Makara Journal of Science
The waste generated in metal coating and leather tanning industries contribute to water pollution owing to the use of Cr metal in production processes. The utilization of lignin from natural base materials in the form of bagasse can reduce unwanted waste from production processes and adsorb Cr ion waste. In this study, lignin was successfully isolated from bagasse waste and then carbonized and applied in Cr metal absorption. Lignin and lignin carbon as an absorbent were characterized using Fourier-transform infrared spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). The ability of bagasse lignin and carbon lignin to absorb Cr ion waste …
Chicken Immune Responses To Vaccination By The Avian Influenza Subtype H5n1 Against Avian Influenza, Ramlah Ramlah, Sri Murtini, Retno Damayanti Soejoedono, Ketut Karuni Nyanakumari Natih, Siti Gusti Ningrum
Chicken Immune Responses To Vaccination By The Avian Influenza Subtype H5n1 Against Avian Influenza, Ramlah Ramlah, Sri Murtini, Retno Damayanti Soejoedono, Ketut Karuni Nyanakumari Natih, Siti Gusti Ningrum
Makara Journal of Science
Avian Influenza (AI) is one of the strategic animal diseases still considered a priority for control by the Indonesian government. This study aimed to examine the immune response of chickens to various types of H5N1 subtype AI vaccines in Indonesia and to determine the correlation of factors influencing the post-vaccination AI antibody response. Serum samples were tested using the hemagglutination inhibition (HI) test with the standard AI antigen subtype H5N1 strain A/Chicken/Barru/BBVM/41-13/2013 (Clade 2.1.3) and strain A/Chicken/Semarang/04141225-07/2014 (Clade 2.3.2). Antibody titer was calculated using the Geometric Mean Titer (GMT). The correlation analyses were performed to assess the correlation of antibody …
The Potency Of Citrus Aurantiifolia Swingle And Sea Salt Solution As A Cleansing Agent For Edible Bird’S Nests, Siti Gusti Ningrum, Adhitya Yoppy Ro Candra, Hana Cipka Pramuda Wardhani
The Potency Of Citrus Aurantiifolia Swingle And Sea Salt Solution As A Cleansing Agent For Edible Bird’S Nests, Siti Gusti Ningrum, Adhitya Yoppy Ro Candra, Hana Cipka Pramuda Wardhani
Makara Journal of Science
The present study aimed to evaluate the potency of Citrus aurantiifolia Swingle and sea salt solution as a promising cleansing agent for edible bird’s nests (EBNs). Ascorbic acid, sodium, and chloride analyses of the C. aurantiifolia Swingle and sea salt solution were conducted using HPLC, ICP-OES, and titrimetry, respectively. The characteristics of physical samples and hydrogen peroxide detection were examined in this study. The reduction activity of the Citrus aurantiifolia Swingle and sea salt solution on the nitrite of 120 white EBNs was studied. This nitrite reduction activity was compared with the available method (standard), drinking water method, 6% C. …
Synthesis And Study Of Anticancer And Antioxidant Activities Of 2-Oxoquinoline Hydrazide Derivatives, Marwa Khalil Mohamed, Ezzeldin Mohamed S. Salem, Ibrahim Ahmed I. Ali
Synthesis And Study Of Anticancer And Antioxidant Activities Of 2-Oxoquinoline Hydrazide Derivatives, Marwa Khalil Mohamed, Ezzeldin Mohamed S. Salem, Ibrahim Ahmed I. Ali
Makara Journal of Science
In this work, hydrazone, thiosemicarbazide, diamide, and dipeptide derivatives were prepared from the glycine and β-alanine hydrazide of 4-hydroxy-2-oxoquinoline. The desired derivative resulted from substitution, hydrazinolysis, condensation, and azide coupling reactions. The fabricated derivatives were screened for anticancer characteristics toward human’s colon carcinoma (HCT-116) cell line using the 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide viability assay, while antioxidant property was examined using an in vitro H2O2 scavenging method. The β-alanine hydrazide derivative 3a showed a remarkable IC50 value of 18.8 μg/mL, whereas its corresponding thiosemicarbazide 5b exhibited moderate activeness with an IC50 value of 26.89 μg/mL. Conversely, …
Diketopiperazine Cyclo-(S-Pro-R-Leu) Produced By Periconia Pseudobyssoides K5 Isolated From Toona Sureni (Meliaceae) And Its Heme Polymerization Inhibition Activity, Azmi Azhari, Desi Harneti, Asri Peni Wulandari, Yeni Mulyani, Sari Purbaya, Aprilia Permata Sari, Galih Bayu Pratama, Unang Supratman, Yoshihito Shiono
Diketopiperazine Cyclo-(S-Pro-R-Leu) Produced By Periconia Pseudobyssoides K5 Isolated From Toona Sureni (Meliaceae) And Its Heme Polymerization Inhibition Activity, Azmi Azhari, Desi Harneti, Asri Peni Wulandari, Yeni Mulyani, Sari Purbaya, Aprilia Permata Sari, Galih Bayu Pratama, Unang Supratman, Yoshihito Shiono
Makara Journal of Science
Fungi endophytes are living microorganisms colonizing inside the internal tissue of a plant and provide ecological benefits for their host. Endophytes provide various metabolites for plant adaptation toward biotic and abiotic stresses and have tremendous pharmacological activities. Toona sureni (T. sureni) (Meliaceae) belongs to the Toona genera and is reported to have antimalarial activity. To determine the compounds produced by the endophytic fungus from this plant, we isolated a compound from Periconia pseudobyssoides (P. pseudobyssoides) K5 endophytes from the stem bark of T. sureni. Diketopiperazine cyclo-(S-Pro-R-Leu), a non-ribosomal peptide, was isolated from brown …
Potential Effect Of Phlorotannins In Brown Algae For Antidiabetic Therapy: Molecular Docking Approach, Melani Sinastri Renagupita, Rahadianto Rahadianto, Efyluk Garianto, Herin Setianingsih
Potential Effect Of Phlorotannins In Brown Algae For Antidiabetic Therapy: Molecular Docking Approach, Melani Sinastri Renagupita, Rahadianto Rahadianto, Efyluk Garianto, Herin Setianingsih
Makara Journal of Science
This study aims to manifest the effect of the active compound phlorotannins in brown algae on decreasing insulin resistance by analyzing the predicted interaction between phlorotannins and protein tyrosine phosphatase 1B (PTP 1B) and estimating the pharmacokinetics and toxicity of the active compound for type 2 diabetes mellitus (DM) therapy. This type of research uses an in silico study to test the effect of using phlorotannins as an active compound in brown algae against PTP 1B inhibition. Starting from preparing materials, i.e., downloading the three-dimensional structure of phlorotannins via PubChem and PTP 1B via RSCB PDB (PDB 1A5Y), molecular docking …
Pva-Sansevieria Trifasciata Fraction Films As Absorbers Of Electromagnetic And Thermal Radiation On Smartphones, Nabiila Rahmani, Gustini Syahbirin, Akhiruddin Maddu, Purwantiningsih Sugita, Auliya Ilmiawati
Pva-Sansevieria Trifasciata Fraction Films As Absorbers Of Electromagnetic And Thermal Radiation On Smartphones, Nabiila Rahmani, Gustini Syahbirin, Akhiruddin Maddu, Purwantiningsih Sugita, Auliya Ilmiawati
Makara Journal of Science
Technological developments have prompted the production of highly advanced smartphones. However, various advanced features cause smartphones to heat up quickly and emit more electromagnetic radiation, which harms human health. Smartphone protection is needed to solve these issues. This study aims to create a film from the S. trifasciata plant based on polyvinyl alcohol (PVA) to reduce electromagnetic and thermal radiation on smartphones. S. trifasciata plants were macerated with acetone and partitioned with n-hexane, dichloromethane, ethyl acetate, and water. The films were made by mixing PVA with the four fractions. Among the four layers of film, the PVA + water …