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Articles 1 - 9 of 9
Full-Text Articles in Life Sciences
Computational Analysis Of Chromophore Tripeptides Followingfusion Of Enhanced Green Fluorescent Protein And Cell-Penetrating Peptides, Silvia Tri Widyaningtyas, Ekawati Betty Pratiwi, Budiman Bela
Computational Analysis Of Chromophore Tripeptides Followingfusion Of Enhanced Green Fluorescent Protein And Cell-Penetrating Peptides, Silvia Tri Widyaningtyas, Ekawati Betty Pratiwi, Budiman Bela
Makara Journal of Science
Cell-penetrating peptides (CPPs) are small peptides that can transfer other materials into a cellular compartment. In this research, we studied the effect of fusion of new CPPs to the N-terminal of enhanced Green Fluorescent Protein eGFP on the ability of the latter to fluoresce. Results showed that the recombinant protein CPPs-eGFP could be successfully expressed in Escherichia coli. In contrast to E. coli expressing wild-type eGFP, which could fluoresce under ultraviolet (UV) or visible light, E. coli expressing CPPs-eGFP lost their ability to fluoresce. PyMol, a molecular visualization system, revealed that fusion of the new CPPs to the N-terminal …
Efficient And Mild Four-Component Process For The Synthesis Of Highly Substituted Dihydro-2-Oxopyrroles Using Zrocl2∙8h2o As An Environmental-Ly Friendly Catalyst, Farzaneh Mohamadpour
Efficient And Mild Four-Component Process For The Synthesis Of Highly Substituted Dihydro-2-Oxopyrroles Using Zrocl2∙8h2o As An Environmental-Ly Friendly Catalyst, Farzaneh Mohamadpour
Makara Journal of Science
This study investigated the catalytic ability of ZrOCl2∙8H2O as a mild, environmentally benign nature, and economical catalyst for the multi-component efficient synthesis of biologically active highly substituted dihydro-2-oxopyrrole derivatives with excellent yields and short reaction times. This procedure has several advantages, including use of mild, nontoxic, and inexpensive catalysts, one-pot synthesis, environmentally benign nature, simple operational procedure, and highly efficient conditions.
Malonic Acid As A Green And Efficient Catalyst For The Mass-Scale Synthesis Of Pyrrole Medicinal Drugs, Farzaneh Mohamadpour
Malonic Acid As A Green And Efficient Catalyst For The Mass-Scale Synthesis Of Pyrrole Medicinal Drugs, Farzaneh Mohamadpour
Makara Journal of Science
A green and naturally biodegradable malonic acid synthesis of highly substituted dihydro-2-oxopyrrole derivatives has been accomplished via one-pot four-condensation of amines (aromatic or aliphatic), dialkyl acetylenedicarboxylate, and formaldehyde under mild reaction conditions. The notable advantages of the present procedure are a green, low cost, and efficient catalyst; operational simplicity; no need for chromatographic purification steps; short reaction times; and good to high yields.
Hepatitis B Surface Antigen And Viral Dna Detection And Prevalence In Nige-Ria, Abazuh Uchenna Desmond, Ohiengbomwan Onaiwu Tola, Adeolu Isaac, Yusuf Mercy
Hepatitis B Surface Antigen And Viral Dna Detection And Prevalence In Nige-Ria, Abazuh Uchenna Desmond, Ohiengbomwan Onaiwu Tola, Adeolu Isaac, Yusuf Mercy
Makara Journal of Science
Hepatitis B infection is a major public health issue with a high mortality rate. It is caused by hepatitis B virus (HBV), a small incomplete hepadnavirus with several open reading frames (ORF). High mutation rates of the HBV ORFs due to the virus’ replicating strategy are associated with the development and emergence of mutant strains, which may result in occult infections that are undetectable by conventional diagnostic assays. In this study, we first investigated the presence and prevalence of hepatitis B surface antigen (HBsAg) and HBV DNA among 204 patients visiting the specialist hospital in Osogbo, Nigeria, by using the …
Removal Of Pb2+ And Cd2+ From Aqueous Solutions Using Pocl3 Cross-Linked Carboxymethyl Derivatives Of Legume Starch, Ayodele Akinterinwa, Ebun Oladele, Albert Adebayo, Olubode Ajayi
Removal Of Pb2+ And Cd2+ From Aqueous Solutions Using Pocl3 Cross-Linked Carboxymethyl Derivatives Of Legume Starch, Ayodele Akinterinwa, Ebun Oladele, Albert Adebayo, Olubode Ajayi
Makara Journal of Science
Starch was extracted from Kwakil beans and cross-linked with POCl3 (1% v/w of starch dry basis [db]). The cross-linked starch (PCS) derivative was carboxymethylated with sodium monochloroacetate (5% to 30% w/w of starch db) to obtain cross-linked carboxymethyl starch (PCCS) derivatives. The derivatives were used in the adsorption of Pb2+ and Cd2+, and the process was monitored using atomic adsorption spectrometer. Carboxymethylation enhanced adsorption of ions (Cd2+, 95% to 96%; Pb, 65% to 94%), and it was more appreciable with Pb2+ than Cd2+ as degree of substitution increased from 0.008 to 0.052. …
Solid Waste Co-Conversion By Hydrothermal Treatment Using Natural Zeolite, Lalak Tarbiyatun Nasyin Maleiva, Chandra Wahyu Purnomo
Solid Waste Co-Conversion By Hydrothermal Treatment Using Natural Zeolite, Lalak Tarbiyatun Nasyin Maleiva, Chandra Wahyu Purnomo
Makara Journal of Science
Hydrothermal treatment is a thermal conversion technology for processing high-moisture-content solid waste to coal-like materials. In this research, mixtures of sawdust and polyethylene terephthalate (PET) waste were treated in a 2000 mL hydrothermal reactor to produce hydrochar and a liquid product. The effects of zeolite addition and temperature variations during the treatment on the product characteristics were investigated. During the treatment, the utilized temperatures were 180, 200, and 220 °C, and the zeolite contents in the mixture were 10 and 20 wt%; the temperature and zeolite content were varied, while the other processing parameters were fixed, i.e., a biomass-to-PET ratio …
Sensitivity Enhancement Of Silicon-On-Insulator Multipath Ring Resonator Using Gold Nanodisk For Sensor Application, Gabriel Dicky, Shidqie Taufiqurrahman, Topik Teguh Estu, Yusuf Nur Wijayanto, Robeth Viktoria Manurung, Dadin Mahmudin, Isa Anshori, Pamungkas Daud
Sensitivity Enhancement Of Silicon-On-Insulator Multipath Ring Resonator Using Gold Nanodisk For Sensor Application, Gabriel Dicky, Shidqie Taufiqurrahman, Topik Teguh Estu, Yusuf Nur Wijayanto, Robeth Viktoria Manurung, Dadin Mahmudin, Isa Anshori, Pamungkas Daud
Makara Journal of Science
Currently, environmental degradation caused by heavy metals has become a serious concern of many countries. To monitor the concentration of heavy metals in the environment, an in-situ sensor that can measure in real time and has high quality, sensitivity, and flexibility is essential. We proposed a modified multipath ring resonator (MPRR) based on silicon-on-insulator technology with additional gold nanodisk (GND) on top of the ring to increase its sensitivity. To prove the effect of GND on the sensitivity of the modified MPRR, finite-difference time-domain simulations were conducted. Results showed that the average sensitivity of the modified MPRR was 675 nm/RIU, …
Key Deposition Parameters For Short-Type Zno Nanosheets Electrodeposited Under Galvanostatic Mode, Gerald Ensang Timuda, Dhimas Harjanto, Wahyu Bambang Widayatno
Key Deposition Parameters For Short-Type Zno Nanosheets Electrodeposited Under Galvanostatic Mode, Gerald Ensang Timuda, Dhimas Harjanto, Wahyu Bambang Widayatno
Makara Journal of Science
Studies on the deposition of ZnO nanosheets grown vertically and perpendicular to conductive substrates have been conducted to obtain tall-type nanosheets (approximately 15 µm in height). However, some applications require short-type nanosheets with a height of about 1µm or less. In this study, short-type ZnO nanosheets were electrodeposited on indium-doped tin oxide substrates under galvanostatic (constant current) mode for a short deposition time. Then, the key parameters to form nanosheet layers with a height in the micrometer order and with good coverage were evaluated. Deposition was performed at 1 mA/cm2 for 60 s. Ar gas was initially bubbled into …
Water Quality Assessment In The Occurrence Of Acanthaster Spp. (Crown-Of-Thorns Starfish, Cots) On Coral Reefs In Menjangan Island, Bali, Indonesia, Novia Arinda Pradisty, Eghbert Elvan Ampou, Rizki Hanintyo
Water Quality Assessment In The Occurrence Of Acanthaster Spp. (Crown-Of-Thorns Starfish, Cots) On Coral Reefs In Menjangan Island, Bali, Indonesia, Novia Arinda Pradisty, Eghbert Elvan Ampou, Rizki Hanintyo
Makara Journal of Science
Aquatic stressors are known to cause biological impairment that can result in biodiversity loss in several Marine Protected Areas (MPA), including in Menjangan Island, West Bali National Park. The objectives of this study were to correlate the changes in water quality parameters with the biological effect of Crown-of-Thorns starfish (CoTS) population dynamics and to assess the most applicable parameters for continuous environmental monitoring. Field observations and surveys were conducted three times in 2017, during the wet season, dry season and season transition, in order to assess the effect of seasonal variability. Redundancy Analysis (RDA) was performed to determine the relationship …