Life Sciences Commons^™

Quantifying The Heterogeneity Of The Immunoglobulin G N-Glycome In An Ageing Australian Population: The Busselton Healthy Ageing Study, Alyce Russell

Theses: Doctorates and Masters

The use of immunoglobulin G N-glycomics to study chronic non-communicable disorders and other complex phenotypes emerged following the Human Genome Project. The consortium discovered that most phenotypes were too complex to be explained by genetics alone. Thus, the biological importance of epigenetics was recognised; heritable modifications to gene expression rather than the genome itself. Nglycosylation is a form of epigenetic regulation known as a post-translational modification. It stabilises the immunoglobulin G structure and alters downstream responses elicited by the antibody and is extensively studied as a candidate biomarker in the post-genomic era.

The N-glycosylation of immunoglobulin G itself is complex, …

Horse Alert Wa, Department Of Agriculture And Food, Western Australia

All other publications

Increasing awareness of emergency horse diseases, their management in Western Australia and practical strategies to minimise the risk of spreading disease. Horse Alert WA has been developed to help participants in the racing, sporting and recreational sectors of the horse industry in Western Australia to prepare for, recognise and respond effectively to an emergency disease that affects horses, such as the equine influenza outbreak in Australia in 2007. This manual provides biosecurity information to minimise the risks of a horse disease establishing and spreading in Western Australia, and guidance on the actions to take if an emergency disease occurs. Some …

Common Regional Pests Of Western Australia, Department Of Agriculture And Food, Western Australia

Bulletins 4000 -

Western Australia is free from many exotic animal and plant pests, diseases and weeds that are present elsewhere in Australia. However, the state does have some unwanted intruders. Of these, many are declared plants or declared animals which, for the sake of convenience, we collectively call declared pests.

Proceedings Of The National Workshop On Footrot, Perth 19-21 August 2003, R K. Mitchell, A R B Higgs, A R. Mercy

Agriculture reports

The financial support of Australian Wool Innovation Ltd (AWI) made it possible for representatives of a range of organisations from across Australia to meet and review ovine footrot. This national workshop held in Perth in August 2003, was the first of its kind for several years and brought together senior researchers, policy makers and producers from all States. The workshop provided an opportunity for the varied approach to footrot control across Australia to be considered in terms of a national approach to footrot control and also for individual States to review their current strategies in the light of experiences in …

Dealing With A Dry Season, Department Of Agriculture And Food, Western Australia

Bulletins 4000 -

Farmers' approaches to adverse seasonal conditions whether they be frost, flood or low rainfall should be to acquire as much information as possible on the immediate agronomic and financial situations and make a judgement on the longer term implications for the following seasons. Once the information has been acquired, in consultation with advisers, it is necessary to construct and implement agronomic and business strategies to deal with individual situations.

The agronomic and stocking options for the dry season supplied in this booklet deal with questions and issues arising from the Year 2000 season, which has been characterised by a mid …

Eradicating Virulent Footrot From Western Australia, R K. Mitchell

Journal of the Department of Agriculture, Western Australia, Series 4

Western Australia has a unique opportunity to eradicate virulent footrot from the State's sheep flock, with only 62 properties or 0.6 per cent of sheep properties currently in quarantine. The majority of Western Australian flocks are now free of virulent footrot, with targeted on-farm and abattoir surveillance used to detect the remaining properties affected by the disease. Bob Mitchell reports on how farmers, industry, and government are working together, with research playing an important part in the eradication campaign.

Virulent Footrot : Mild Or Severe?, Laurie Depiazzi

Journal of the Department of Agriculture, Western Australia, Series 4

The footrot eradication scheme in Western Australia has resulted in a low prevalence of severe footrot.

To appreciate the achievement, we need to understand what exactly is being eradicated. 'S' strains of Dichelorbacter nodosus, the infectious bacterium of footrot, are the target of footrot eradication. Laurie Depiazzi examines the basis for eradicating 'S' strains.

Sharing Information Benefits The Meat Industry, Michael Paton

Journal of the Department of Agriculture, Western Australia, Series 4

Cronic health problems of livestock, seldom detected on farms, reduce the efficiency of abattoirs and returns to producers. But a major project providing information to producers from abattoirs is indicating how everyone could benefit from feedback.

Quality Wool Production At Lower Cost, Peter Metcalfe

Journal of the Department of Agriculture, Western Australia, Series 4

Low wool prices are forcing farmers to reduce their sheep management costs but, fortunately, cost cutting is not resulting in lower wool production, poorer wool quality or lessened sheep care on the best wool growing properties.

Progress Toward Eradication Of Virulent Footrot, Bob Mitchell

Journal of the Department of Agriculture, Western Australia, Series 4

Western Australia is well placed to eradicate virulent footrot from the State's sheep and goat populations.

Between 1950 and 1993 the proportion of sheep flocks with footrot fell from about 15 per cent to less than 2 percent, and the 1990-92 outbreak has been turned around. One hundred and eighty properties (]. 7 per cent) of flocks, mostly in the high rainfall South-West, are in quarantine for footrot today.

This high level of footrot control is the result of strong support from the sheep industry and years of good cooperation between farmers and the Department of Agriculture.

Western Australia leads …

Are Foxes Serious Predators Of Stock?, Peter Mawson, John Long

Journal of the Department of Agriculture, Western Australia, Series 4

Commercial farming of goats for mohair, cashmere and meat production is a rapidly developing industry in the south-west of Western Australia.

In this article, the authors discuss the results of two studies conducted by the Agriculture Protection Board in which the levels of predation of kids and lambs by foxes in commercial goat flocks, and an experimental multiple-birth genotype sheep flock in the southwest of Western Australia, were measured.

Understanding The Importance Of Eperythrozoon Ovis Infection In Sheep, Marc Kabay

Journal of the Department of Agriculture, Western Australia, Series 4

Assigning priorities for research on sheep diseases relies in part on understanding the prevalence and economic impact of each disease.

Eperythrozoon ovis infection in sheep, for example is a common, but not costly, disease.

Getting The Best Out Of Weaner Sheep In The Eastern Wheatbelt, Sally Revell

Journal of the Department of Agriculture, Western Australia, Series 4

A study of the growth of Merino weaner flocks over summer and autumn in Western Australia 's eastern wheatbelt during 1989 and 1990 has identified efficient weaner management strategies, and provided a basis for future research and extension needs of this area. The average liveweight of several weaner flocks was unexpectedly low at the start of summer. Weaner flocks may need to be supplemented before the start of summer to prevent undue weight loss at this time.

Veterinary Consultancy Boosts Piggery Profits, Ashley Mercy

Journal of the Department of Agriculture, Western Australia, Series 4

A pilot Pig Herd Health Management Scheme co-ordinated by the Department of Agriculture has stimulated much increased involvement of veterinarians in the Western Australian pig industry. Co-ordinated by Ashley Mercy, principal veterinary officer (epidemiology) horn 1985 to 1989, the scheme demonstrated the value of having regular visits from veterinary consultants and in implementing programs to prevent disease and production problems occurring in herds.

Breeding Phomopsis-Resistant Lupins, John Sylvester Gladstones

Journal of the Department of Agriculture, Western Australia, Series 4

The release of Gungurru and Yorrel lupins marks the coming of age of the narrow-leafed lupin as a crop plantt. These are the first cultivars of the species th have substantial resistance to Phomopsis stem blight, which will make the stubbles much safer for grazing stock.

This article describes the new lupins, their background, and how they were bred. It also acknowledges the contributions of colleagues who helped in important ways.

Economic Impact Of Growing Phomopsis-Resistant Lupins, J M. Warren, Jeremy Allen, Wallace Cowling

Journal of the Department of Agriculture, Western Australia, Series 4

The planting of Phomopsis-resistant lupins will increase net farm income. They will also alter the traditional blend of pastures and cropping, depending on grain and wool prices. In mixed farming areas of Western Australia's southern wheatbelt, they will allow more land to be sown to lupins rather than cereals on farms in which the lack of sheep feed over summer severely restricts wool production.

The benefits of Phompsis-resistant lupins arise from a reduction in sheep deaths due to lupinosis, a longer safe grazing period (free from lupinosis) on lupin stubbles, a decrease in the need for supplementary sheep feed over …

Leaf Diseases Of Wheat And Time Of Sowing, J M. Wilson

Journal of the Department of Agriculture, Western Australia, Series 4

Leaf diseases of wheat can be avoided by delaying the planting of a crop, but this often leads to reduced yield because the benefits of early sowing usually outweigh anylosses caused by leaf disease.

However, it is only in exceptional circumstances that farmers need to consider leaf disease when making decisions about planting date, as this article shows. Most examples are taken from department of Agriculture trials in its northern advisory region, but the principals apply to other agricultural areas.

Farmers' Estimations Of Sheep Weights To Calculate Drench Dose, R B. Besier, Diane Hopkins

Journal of the Department of Agriculture, Western Australia, Series 4

Undersosing with drenches is a mojor cause of anthelmintic (drench) resistance in worm parasites of sheep.

When farmers use a drench at less than the recommended dose rate, some worms may survive, and their ability to resist treatment with the chemical involved is passed to their offspring. Over a period of time, matings between worms with different degrees of resistance can produce individuals able to resist the drench at the recommended dose rate or even higher.

Farmers must use adequate dose rates so that worms do not have a chance to survive treatment.

Evaluation Of The Crack Approach For The Control Of Drench Resistance In Sheep Worms, J R. Edwards, Helen Chapman, Jon Dunsmore

Journal of the Department of Agriculture, Western Australia, Series 4

The Department of Agriculture launched the CRACK approach to worm control in September 1985 in response to finding that anthelmintic (drench) resistant worms were present on 68 per cent of a random selection of Western Australian sheep farms.

The high cost of internal parasites in terms of lost production and drench costs, together with the high prevalence of resistant worms of farms, confirmed that changes were needed to existing parasite control measures in sheep.l

Virus Diseases Of Lupins Virus Diseases Of Pastures, R A.C Jones, A. Baker, K. Clarke, F. Jones

Experimental Summaries - Plant Research

Virus diseases of lupins.

Bean yellow mosaic virus and cucumber mosaic virus

Effect of CMV isolate

Effect of pod position

Effect of dry conditions on establishment

Effect of cultivar on seed transmission rates

Effect of reflective mulch

Survey of commercial seed stocks.

Virus disease of pastures

Bean yellow mosaic virus and cucumber and alfalfa mosaic viruses

Symptoms

Distribution

Seed-borne infection

Persistence

Recommendations for control

Lupin phyllody disorder

Barley yellow dwarf virus

Publications

Sheep Lice : Prospects For Eradication, F C. Wilkinson

Journal of the Department of Agriculture, Western Australia, Series 4

Sheep biting lice have been controlled over the past 86 years in Western australia by a combination of routine insecticidal treatment after shearing and action by the department of Agriculture officers under legislation.

In July 1987 the sheep industry and the State Government will implement a plan to eradicate lice from sheep flocks in the agricultural areas and eventually in the pastoral areas. To achieve this the co-operation of many sectors of the industry will be required. Assuming co-operation is forthcoming, it is possible that by 1996 wool from agricultural areas will be free of lice and insecticidal treatment form …

Annual Ryegrass Toxicity Research Update, A G P Brown, P. Vogal

Journal of the Department of Agriculture, Western Australia, Series 4

Annual ryegrass toxicity (ARGT) is a complex disease that kills sheep and cattle grazing pastures which contain infected ryegrass. The disease results when a nematode (Anguina agrostis) and a batcerium (Corynebacterium sp.) invade annual ryegrass and cause the seed heads to become toxic as the grass dries off.

The bacterium produces a complex toxin of 18 glycolipid compounds or corynetoxins which have been found to be virtually identical to the antibiotic tunicamycin.

Preventing Lupinosis With Phomopsis-Resistant Lupins, Jeremy G. Allen, W. A. Cowling

Journal of the Department of Agriculture, Western Australia, Series 4

Lupinosis is one of the major livestock siseases in Western Australia. It is caused by stock eating toxins produced by the fungus Phomopsis leptostromiformis which colonises the stems of dead lupin plants.

In 975, the Department of Agriculture started a breeding programme to develop Phompsis-resistant lupins to overcome or control lupinosis. In the previous issue of this Journal the results of small plot evaluations of new lines of Phompsis-resistant lupins developed in this programme were reported. This article describes the first trial involving grazing of Phompsis-resistant lupins.

A Survey Of Drench Resistance In Sheep Worms, J R. Edwards, R. Wroth, G. C. De Chaneet, R. B. Besier, J. Karlsson, P. W. Morcombe, D. Roberts, G. Dalton-Morgan

Journal of the Department of Agriculture, Western Australia, Series 4

Sheep worms which are resistant to chemical drenches have been detected with increasing freuency is Western Australia's south-western farming areas between 977 and 1980. These worms have anthelmintic resistance and such genetis resistance puts essential internal parasite control practices at risk.

This prompted veterinarians in the Esperance, Albany, Bunbury, Geraldton and Northam areas to survey farms to determine the prevalence of resistance to drenches and to define those sheep management practices which encourage its development.

This article describes the survey which was conducted to assess the extent of drench resistance, what causes its build-up and how it can be controlled …

Some Basics Of Marron Production, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

marron are native to the South-West of Western Australia, and are keenly sought by inland fisher-men. However, supplies do not equal the apparent demand.

One solution is to cultivate marron in farm dams, or more intensively as a commercial enterprise.

This article suggests a few guidelines for marron production.

Wheat Rust Epidemics, A G P Brown, J. T. Reeves

Journal of the Department of Agriculture, Western Australia, Series 4

Stem rust of wheat is probably the most damaging plant disease in the world. The rust fungus attacks stems, leaves and heads, producing characteristic red-brown pustules which affect the plant's ability to fill out the grain. Yield loss is directly related to the amount of rust in the crop and the length of time the crop is infected.

In Western Australia it is not uncommon to find rust on crops in mid-October, but usually there is negligible loss of yield. In fact this pattern is quite normal throughout the world: In general, rust arrives too late to cause an epidemic. …

Reproductive Wastage Among Merino Ewe Flocks. 2. Non-Clover Areas, T Marshall, B. R. Beetson, R. J. Lightfoot, G. R. Mcmullen

Journal of the Department of Agriculture, Western Australia, Series 4

This research sought to define the reasons for low fertility among Merino ewes in Western Australia.

This first article looks at wastage in Non-Clover areas

Dairying In W.A., Department Of Agriculture And Food, Western Australia

Bulletins - 3000 - 3999

Western Australia has a small dairy industry compared with its other rural production. However, the industry has consolidated over recent years.Tree clearing and pasture development on existing holdings and the amalgamation of small dairy farms has led to a rapid increase in the area of pasture per farm. The trend in Western Australia is towards bigger herds, more efficient dairies, more fodder conservation and increasing production per cow and per hectare. Commercial dairy farming in Western Australia is confined to the south-western corner of the State, south of Perth, extending in a 50-kilometre-wide strip along the coast to 50 kilometres …

Beef In W.A., Department Of Agriculture And Food, Western Australia

Bulletins - 3000 - 3999

There are four major regions of beef production in Western Australia, each suited to its own type of husbandry. In such a large area, climate plays an important part in limiting production off pasture and this is reflected in the different patterns of production that have emerged from the accumulated experience of working in these areas.

Clover Disease : What Do We Know And What Can We Do, T Marshall

Journal of the Department of Agriculture, Western Australia, Series 4

A review of 30 years' study and practical experience of clover disease in Western Australia—and a summary of current recommendations for reducing problems in sheep grazing pastures based on oestrogenic subterranean clover.