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The Role Of Accessory Domain In Cpsa Function And Capsule Production In Group B Streptococcus, Gina Difederico
The Role Of Accessory Domain In Cpsa Function And Capsule Production In Group B Streptococcus, Gina Difederico
Honors College
Group B Streptococcus (GBS) can be found in the vaginal and genitourinary tract of females, as well as the genitourinary tract of males, where it behaves as a commensal organism. However, as an opportunistic pathogen, GBS has the capability to infect the immunocompromised, making it a major threat to neonates and fetuses. The pathogen can be passed from mother to baby either in utero or during birth. The capsule, which is a polysaccharide coating on the outside of the cell, is considered the most important virulence factor in GBS.Expression of capsule plays a role in evasion of the host immune …