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Chipathlon: A Competitive Assessment For Gene Regulation Tools., Avi Knecht, Adam Caprez, Istvan Ladunga
Chipathlon: A Competitive Assessment For Gene Regulation Tools., Avi Knecht, Adam Caprez, Istvan Ladunga
UCARE Research Products
When gene regulation of the cell cycle malfunctions, it frequently causes cancer.
Adult, differentiated cells can be reprogrammed to induced pluripotent stem cell; which can then be reprogrammed to heart muscle, skin, etc, to repair damaged tissue (to limited extent in clinical practice).
ChIPathlon: Evaluate the performance of all transcription factor mapping (peak calling) methods. To this end, we will develop a scalable and easy to use super computing pipeline to stage data, compare many different peak calling and differential binding site tools, and store all results into a single database.