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Multimodal Neuron Classification Based On Morphology And Electrophysiology, Aqib Ahmad
Multimodal Neuron Classification Based On Morphology And Electrophysiology, Aqib Ahmad
Graduate Theses, Dissertations, and Problem Reports
Categorizing neurons into different types to understand neural circuits and ultimately brain function is a major challenge in neuroscience. While electrical properties are critical in defining a neuron, its morphology is equally important. Advancements in single-cell analysis methods have allowed neuroscientists to simultaneously capture multiple data modalities from a neuron. We propose a method to classify neurons using both morphological structure and electrophysiology. Current approaches are based on a limited analysis of morphological features. We propose to use a new graph neural network to learn representations that more comprehensively account for the complexity of the shape of neuronal structures. In …