Life Sciences Commons^™

An Investigation Of Information Structures In Dna, Joel Mohrmann

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

The information-containing nature of the DNA molecule has been long known and observed. One technique for quantifying the relationships existing within the information contained in DNA sequences is an entity from information theory known as the average mutual information (AMI) profile. This investigation sought to use principally the AMI profile along with a few other metrics to explore the structure of the information contained in DNA sequences.

Treating DNA sequences as an information source, several computational methods were employed to model their information structure. Maximum likelihood and maximum a posteriori estimators were used to predict missing bases in DNA sequences. …

Collaborative Research: North East Cyberinfrastructure Consortium, Michael Eckardt, Vicki Nemeth, Carolyn Mattingly

University of Maine Office of Research Administration: Grant Reports

The North East Cyberinfrastructure Consortium has finished its third year of Track-2 funding. In this report we summarize our overall progress and progress for Year 3.

In 2006, we began to organize as the five North Eastern EPSCoR states (ME, NH, VT, Rl, DE) around cyberinfrastructure. The box below describes the state of cyberinfrastructure in 2008 by which time we had developed the North East Cyberinfrastructure Consortium to position ourselves for grant opportunities that would help us to address our cyber deficits.

The Track-2 collaborative proposal submitted in January 2009 was designed to address these barriers in order enable our …