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Full-Text Articles in Life Sciences
Axonal Activity In Vivo: Technical Considerations And Implications For The Exploration Of Neural Circuits In Freely Moving Animals, Jeremy M. Barry
Axonal Activity In Vivo: Technical Considerations And Implications For The Exploration Of Neural Circuits In Freely Moving Animals, Jeremy M. Barry
Dartmouth Scholarship
While extracellular somatic action potentials from freely moving rats have been well characterized, axonal activity has not. We have recently reported extracellular tetrode recordings of short duration waveforms (SDWs) with an average peak-trough duration less than 172μs. These waveforms have significantly shorter duration than somatic action potentials and tend to be triphasic. The present review discusses further data that suggests SDWs are representative of axonal activity, how this characterization allows for more accurate classification of somatic activity and could serve as a means of exploring signal integration in neural circuits. The review also discusses how axons may function as more …
Spike Field Coherence (Sfc) For Ripples In Rat Hippocampus, Pranav Singla
Spike Field Coherence (Sfc) For Ripples In Rat Hippocampus, Pranav Singla
Honors Scholar Theses
The aim of this project was to determine coherence between two types of neural recordings which can be obtained from the rat hippocampus: spikes and local field potentials. Extracellular recording makes it possible to determine spiking activity from individual neurons in the vicinity of the recording electrode. Local field potential recording gives a combined activity of many neurons (thousands) at once to determine an overall picture of the coordination of the cells in real time. Here we examine the relationship between these two signals, focusing on place cells which spike at their maximal rate only at certain positions in physical …