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Investigation Of Memory Related Cortical Thalamic Circuitry In The Human Brain, Puck C. Reeders
Investigation Of Memory Related Cortical Thalamic Circuitry In The Human Brain, Puck C. Reeders
FIU Electronic Theses and Dissertations
This dissertation examined the role of medial prefrontal cortex (mPFC) and the hippocampus (HC) in episodic memory, and provides a novel approach to identify the midline thalamus mediating mPFC-HC interactions in humans. The mPFC and HC are critical to the temporal organization of episodic memory, and these interactions are disrupted in several mental health and neurological disorders. In the first study, I provide evidence that the mPFC is involved in ordinal retrieval, and the HC is active in temporal context retrieval in remembering the order of when events happen. In the second study, I focus on the anatomical basis of …