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Life Sciences Commons

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Chemicals and Drugs

Stephen F. Austin State University

Conference

2021

Articles 1 - 2 of 2

Full-Text Articles in Life Sciences

Expression And Purification Of Hpep Inhibitor Peptide, Olivia Plaza Apr 2021

Expression And Purification Of Hpep Inhibitor Peptide, Olivia Plaza

Undergraduate Research Conference

The enzyme human prolyl peptidase, or hPEP, has been linked to many processes within the brain, including breaking down neural peptides. A bovine milk protein, a-s1-casein (see above), has been found to inhibit hPEP in colon cancer cells. A 68 amino acid long section (bolded) of a-s1- casein containing the inhibitor region was cloned. The casein fragment expression was optimized for expression of the peptide. The purpose for optimizing expression is to have much of it on hand to utilize in further studies on its inhibitory properties on hPEP. By using this fragment of casein, one can study the structure …


Biotransformation Of Hbe And Other Benzofuran Derivatives, Hannah Trauger Apr 2021

Biotransformation Of Hbe And Other Benzofuran Derivatives, Hannah Trauger

Undergraduate Research Conference

No abstract provided.