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Stretch Activation During Fatigue Improves Relative Force Production In Fast-Contracting Mouse Skeletal Muscle Fibers, Philip C. Woods
Stretch Activation During Fatigue Improves Relative Force Production In Fast-Contracting Mouse Skeletal Muscle Fibers, Philip C. Woods
Masters Theses
Stretch activation (FSA) is the delayed increase in fiber specific tension (force per cross-sectional area) following a rapid stretch and can improve muscle performance during repetitive cyclical contractions. Historically considered minimal in skeletal muscle, our recent work showed the ratio ofstretch- to calcium-activated specific tension (FSA/F0) increased from 10 to 40% with greater inorganic phosphate (Pi) levels in soleus muscle fibers (Straight et al., 2019). Given Pi increases with muscle fatigue, we hypothesize that FSA helps maintain force generation during fatigue. To test this, FSA, induced by a stretch of 0.5% …