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Articles 1 - 12 of 12
Full-Text Articles in Life Sciences
Comparison Of Semi-Automated And Manual Differential Separation Methods For Mock Sexual Assault Samples, Stephanie Rink
Comparison Of Semi-Automated And Manual Differential Separation Methods For Mock Sexual Assault Samples, Stephanie Rink
Master of Science in Forensic Science Directed Research Projects
In the event of a sexual assault, separation of suspect from victim DNA is possible through differential extraction if the evidentiary mixture consists of female epithelial cells and male spermatozoa. The basis of differential extraction is the differing properties of epithelial and sperm cell membranes, specifically the comparative sturdiness of the proteins making up the sperm head containing the male DNA. Effective retrieval and separation of male and female DNA fractions is important in generating high-quality STR profiles that can be utilized in identifying suspects in a sexual assault case. Differential extraction has been conventionally performed using Proteinase K (PK) …
Exploring The Connection Between The Spontaneous Regression Seen In Neuroblastomas, Hypertumors, And Reactive Oxygen Species, Shahad Musa, Manitha Mulpuru
Exploring The Connection Between The Spontaneous Regression Seen In Neuroblastomas, Hypertumors, And Reactive Oxygen Species, Shahad Musa, Manitha Mulpuru
AUCTUS: The Journal of Undergraduate Research and Creative Scholarship
Peto’s Paradox is defined as the lack of correlation between larger animals and cancer risk. Under the assumption that all cells have equal risk of becoming cancerous, larger animals should have greater rates of cancer. However, the inverse is true. Determining the cause of this variation may allow a supplemental approach to cancer treatment. A combination of two reasons may account for this correlation including hypertumors and metabolism. Hypertumors, or cheater cells, are hypothesized to suppress cancer growth through spontaneous autophagic degradation and overexpression of the RAS g-protein. Both of these characteristics are exhibited in Neuroblastomas. An anticancer drug used …
Erbb3 Signaling And Its Effect On Spheroid Formation In Ovarian Cancer, Muskan Bansal, Danielle Burke, Mara P. Steinkamp
Erbb3 Signaling And Its Effect On Spheroid Formation In Ovarian Cancer, Muskan Bansal, Danielle Burke, Mara P. Steinkamp
AUCTUS: The Journal of Undergraduate Research and Creative Scholarship
ErbB3 is a receptor tyrosine kinase in the epidermal growth factor receptor (EGFR) family. Like other family members, it has an extracellular ligand-binding domain, a transmembrane domain, and an intracellular kinase domain. ErbB3 requires interactions with other receptors and dimerizes with ErbB2 and MET, to activate downstream signaling pathways. Mutations in the ErbB3 gene within the extracellular and kinase domains have been identified in many cancer types. To understand the impact of ErbB3 on cancer growth and metastasis, the human ovarian cancer cell line, OVCAR8, was used as a model. Parental OVCAR8 cells that express ErbB2 and ErbB3 were compared …
Yap Functions Via Tead Mediated Transcriptional Activation In Hepatoblastoma Pathogenesis, Junyan Tao 8598903, Pin Liu, Jie Zhang, Sucha Singh, Xin Chen, Na Zhan, Satdarshan (Paul) Singh Monga
Yap Functions Via Tead Mediated Transcriptional Activation In Hepatoblastoma Pathogenesis, Junyan Tao 8598903, Pin Liu, Jie Zhang, Sucha Singh, Xin Chen, Na Zhan, Satdarshan (Paul) Singh Monga
Hepatobiliary Cancers: Pathobiology and Translational Advances
No abstract provided.
Survival Model Of Intrahepatic Cholangiocarcinoma; Sex As A Biological Variable, Mary A. Phillippi, Justin L. Mott, Cody J. Wehrkamp, Ying Xie, David Oupicky, Ashley M. Mohr, Bailey A. Stringham
Survival Model Of Intrahepatic Cholangiocarcinoma; Sex As A Biological Variable, Mary A. Phillippi, Justin L. Mott, Cody J. Wehrkamp, Ying Xie, David Oupicky, Ashley M. Mohr, Bailey A. Stringham
Hepatobiliary Cancers: Pathobiology and Translational Advances
No abstract provided.
Ibrutinib In Combination With Sorafenib Synergistically Inhibits Proliferation And Survival Of Hepatocellular Carcinoma Cells By Targeting Egfr Signaling Pathway, Cho-Hao Lin, Nissar Wani, Khadija Elkholy, Kalpana Ghoshal
Ibrutinib In Combination With Sorafenib Synergistically Inhibits Proliferation And Survival Of Hepatocellular Carcinoma Cells By Targeting Egfr Signaling Pathway, Cho-Hao Lin, Nissar Wani, Khadija Elkholy, Kalpana Ghoshal
Hepatobiliary Cancers: Pathobiology and Translational Advances
No abstract provided.
Convergence Of Wnt/Beta-Catenin And Mtor Signaling In Liver Physiology And Hepatocellular Carcinoma, Adeola O. Adebayo Michael, Junyan Tao, Satdarshan P. Monga
Convergence Of Wnt/Beta-Catenin And Mtor Signaling In Liver Physiology And Hepatocellular Carcinoma, Adeola O. Adebayo Michael, Junyan Tao, Satdarshan P. Monga
Hepatobiliary Cancers: Pathobiology and Translational Advances
No abstract provided.
Oncogenic Nelfe Enhances Myc-Induced Hepatocellular Carcinogenesis, Hien Dang, Atsushi Takai, Marshonna Forgues, Yosawat Pomyen, Haiwei Mou, Wen Xue, Debashish Ray, Kevn Ha, Quiad Morris, Timothy Hughes, Xin Wei Wang
Oncogenic Nelfe Enhances Myc-Induced Hepatocellular Carcinogenesis, Hien Dang, Atsushi Takai, Marshonna Forgues, Yosawat Pomyen, Haiwei Mou, Wen Xue, Debashish Ray, Kevn Ha, Quiad Morris, Timothy Hughes, Xin Wei Wang
Hepatobiliary Cancers: Pathobiology and Translational Advances
No abstract provided.
Commonly Used H1 And H2 Histamine Receptor (Hr) Blockers Decrease Cholangiocarcinoma Xenograft Tumor Growth, Angiogenesis And Emt, Lindsey Kennedy, Laura Hargrove, Jennifer Demieville, Walker Karstens, Steven Smith, Heather Francis
Commonly Used H1 And H2 Histamine Receptor (Hr) Blockers Decrease Cholangiocarcinoma Xenograft Tumor Growth, Angiogenesis And Emt, Lindsey Kennedy, Laura Hargrove, Jennifer Demieville, Walker Karstens, Steven Smith, Heather Francis
Hepatobiliary Cancers: Pathobiology and Translational Advances
No abstract provided.
Hepatocyte-Specific Deletion Of Tristetraprolin Family Of Rna Binding Proteins Result In The Development Of Hepatocellular Carcinomas, Sonika Patial
Hepatocyte-Specific Deletion Of Tristetraprolin Family Of Rna Binding Proteins Result In The Development Of Hepatocellular Carcinomas, Sonika Patial
Hepatobiliary Cancers: Pathobiology and Translational Advances
No abstract provided.
The Role Of Kinase Fusion Dnajb1-Prkaca In Fibrolamellar Hepatocellular Carcinoma, Yi Guo
The Role Of Kinase Fusion Dnajb1-Prkaca In Fibrolamellar Hepatocellular Carcinoma, Yi Guo
Hepatobiliary Cancers: Pathobiology and Translational Advances
No abstract provided.
Kruppel-Like Factor 2 In Cholangiocarcinoma, Cody J. Wehrkamp, Justin L. Mott
Kruppel-Like Factor 2 In Cholangiocarcinoma, Cody J. Wehrkamp, Justin L. Mott
Hepatobiliary Cancers: Pathobiology and Translational Advances
No abstract provided.