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Developmental Immunity Of The Skeletal Elements Of The Weberian Apparatus To The Effects Of Exogenous Estrogen (17-Β Estradiol), A Known Disruptor Of Cartliage Development, Bailey Jordan Wetherell
Developmental Immunity Of The Skeletal Elements Of The Weberian Apparatus To The Effects Of Exogenous Estrogen (17-Β Estradiol), A Known Disruptor Of Cartliage Development, Bailey Jordan Wetherell
Honors Program Theses
Proper vertebrate development is controlled by a tightly regulated sequence of gene activation and repression. Exposure to both endogenous (hormones, gene products) and exogenous (environmental chemicals, toxins, etc.) substances during development can have profound effects on morphology by altering growth, cell fate, cell differentiation, and cell migration. Waterways have long been hot-spots for chemical and toxin accumulation, due to runoff and waste dumping. Growing concern is being paid to endocrine disruptors, like estrogen (17β-estradiol), which are found in increasing levels in rivers and streams. Endocrine disruptors are known to cause a varied number of defects in fish species, but the …