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Full-Text Articles in Life Sciences

Two New Species Of Euscorpius From Euboea Island, Greece (Scorpiones: Euscorpiidae), Victor Fet, Michael E. Soleglad, Aristeidis Parmakelis, Panayiota Kotsakiozi, Iasmi Stathi May 2014

Two New Species Of Euscorpius From Euboea Island, Greece (Scorpiones: Euscorpiidae), Victor Fet, Michael E. Soleglad, Aristeidis Parmakelis, Panayiota Kotsakiozi, Iasmi Stathi

Biological Sciences Faculty Research

We describe two new species of the genus Euscorpius from Euboea Island, Greece: E. birulai sp.n. (Agia Triada Cave) and E. mylonasi sp.n. (Mt. Dirfi). The cave species E. birulai sp.n. is morphologically close to E. koschewnikowi Birula, 1900 from Mt. Athos, Greece. Species-level divergence of E. mylonasi sp.n. is also confirmed by multiple DNA markers. According to DNA data, an undescribed population from the nearby Skyros Island is closely related to E. mylonasi sp.n.


Chmp1 Negatively Regulates Epidermal Growth Factor Signaling In The Drosophila Wing, Meagan Elisabeth Valentine Jan 2014

Chmp1 Negatively Regulates Epidermal Growth Factor Signaling In The Drosophila Wing, Meagan Elisabeth Valentine

Theses, Dissertations and Capstones

A critical step in cellular signaling through transmembrane receptors is the down-regulation of activated receptors through the multivesicular body (MVB) pathway to the lysosome. MVB generation is mediated by the highly conserved ESCRT (0, I, II, and III) protein complexes. Though the ESCRT-III complex provides the core function of the ESCRT machinery, it is the least characterized of the ESCRT complexes. The Chmp1 protein is an ESCRT-III component and a putative tumor suppressor that has been linked to pancreatic and renal cancers in humans. However, published data on Chmp1 activity are conflicting and its role during tissue development is not …