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Articles 1 - 7 of 7
Full-Text Articles in Life Sciences
Stochastic Analysis Of A Mammalian Circadian Clock Model: Small Protein Number Effects, David W. Morgens, Blerta Shtylla
Stochastic Analysis Of A Mammalian Circadian Clock Model: Small Protein Number Effects, David W. Morgens, Blerta Shtylla
Spora: A Journal of Biomathematics
The circadian clock, responsible for coordinating organism function with daily and seasonal changes in the day-night cycle, is controlled by a complex protein network that constitutes a robust biochemical oscillator. Deterministic ordinary differential equation models have been used extensively to model the behavior of these central clocks. However, due to the small number of proteins involved in the circadian oscillations, mathematical models that track stochastic variations in the numbers of clock proteins may reveal more complex and biologically relevant behaviors. In this paper, we compare the response of a robust yet detailed deterministic model for the mammalian circadian clock with …
Examining The Electrical Excitation, Calcium Signaling, And Mechanical Contraction Cycle In A Heart Cell, Kristen Deetz, Nygel Foster, Darius Leftwich, Chad Meyer, Shalin Patel, Carlos Barajas, Matthias K. Gobbert, Zana Coulibaly
Examining The Electrical Excitation, Calcium Signaling, And Mechanical Contraction Cycle In A Heart Cell, Kristen Deetz, Nygel Foster, Darius Leftwich, Chad Meyer, Shalin Patel, Carlos Barajas, Matthias K. Gobbert, Zana Coulibaly
Spora: A Journal of Biomathematics
As the leading cause of death in the United States, heart disease has become a principal concern in modern society. Cardiac arrhythmias can be caused by a dysregulation of calcium dynamics in cardiomyocytes. Calcium dysregulation, however, is not yet fully understood and is not easily predicted; this provides motivation for the subsequent research. Excitation-contraction coupling (ECC) is the process through which cardiomyocytes undergo contraction from an action potential. Calcium induced calcium release (CICR) is the mechanism through which electrical excitation is coupled with mechanical contraction through calcium signaling. The study of the interplay between electrical excitation, calcium signaling, and mechanical …
Heads And Tails, Julie Simons
Heads And Tails, Julie Simons
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling Cdc42 Oscillation In Fission Yeast, Bin Xu
Modeling Cdc42 Oscillation In Fission Yeast, Bin Xu
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling Microtubule-Based Transport In The Frog Egg Cell, Maria-Veronica Ciocanel
Modeling Microtubule-Based Transport In The Frog Egg Cell, Maria-Veronica Ciocanel
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Development Of Epithelial Tissues: How Are Cleavage Planes Chosen?, Ying Xin
Development Of Epithelial Tissues: How Are Cleavage Planes Chosen?, Ying Xin
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Mathematical Medicine: Modeling Disease And Treatment, Lisette Depillis
Mathematical Medicine: Modeling Disease And Treatment, Lisette Depillis
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.