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Articles 1 - 10 of 10
Full-Text Articles in Life Sciences
Unusual Structure Of A Human Middle Repetitive Dna, Duminda D. Ratnasinghe
Unusual Structure Of A Human Middle Repetitive Dna, Duminda D. Ratnasinghe
Electronic Theses and Dissertations
The L2Hs sequences are a polymorphic, interspersed, middle repetitive DNA family unique to human genomes. Genomic fingerprinting indicates that these DNAs vary from one individual to another and between tissues of the same individual. Sequence analysis reveals that they are AT-rich (76%) and contain many unusual sequence arrangements (palindromes, inverted and direct repeats). These sequence properties confer on the L2Hs elements the potential to fold into non-B-form structures, a characteristic of recombination hot spots. To test this hypothesis carbodiimide, osmium tetroxide and S$\sb1$ nuclease were used as single-strand specific probes to study a recombinant plasmid, pN6.4.39, containing a single L2Hs …
Inhibition Of Cytochrome P-450 But Not Neutrophil Depletion Prevents The Pulmonary Toxicity Associated With 1-Nitronaphthalene, Steven Michael Green
Inhibition Of Cytochrome P-450 But Not Neutrophil Depletion Prevents The Pulmonary Toxicity Associated With 1-Nitronaphthalene, Steven Michael Green
Masters Theses
1-Nitronaphthalene (1-NN) is an environmental contaminant that has been shown to cause pulmonary toxicity in rodents. To examine the contribution of cytochrome P-450 to the metabolism and subsequent toxicity of 1-NN, rats were pretreated with chloramphenicol, a suicide substrate of P-450. To determine if inflammation plays a role in 1-NN toxicity, rats were pretreated with cyclophosphamide to deplete neutrophils. In both experiments, morphological analysis of the lower airways was performed with light and electron microscopy. A second group of animals was examined for biochemical indicators of inflammation and cell damage. The parameters examined were cell content, protein content and lactate …
The Isolation And Identification Of Polyphenolics From Grape Seeds And Their Activity Towards Specific Cell Lines, Joseph A. Reddy
The Isolation And Identification Of Polyphenolics From Grape Seeds And Their Activity Towards Specific Cell Lines, Joseph A. Reddy
Chemistry & Biochemistry Theses & Dissertations
Grape seed extract is being marketed in France for cardiovascular use and skin care. The active constituents of both these drugs are certain polyphenols called procyanidins. A similar seed extract has now been obtained from Virginia Chardonnay grape seeds. Ten of the major components in this extract have been isolated in their pure form by the semi-preparative HPLC separation on a YMC ODS-AQ (Octadecylsilane-AQ) column. The ODS-Aq column has been shown to have a better resolving capacity compared to the Spherisorb ODS (Octadecylsilane) column previously described in the literature. This has been attributed to the ODSAQ support which has both …
The Cytotoxic Effect Of Tropical Plants On Human And Rat Hepatoma Cells, Mark Tafazoli
The Cytotoxic Effect Of Tropical Plants On Human And Rat Hepatoma Cells, Mark Tafazoli
Honors Capstone Projects and Theses
No abstract provided.
Analysis Of The Proteoglycan Content In Fresh And Cryopreserved Porcine Cardiovascular Tissues, Yun Hee Shon
Analysis Of The Proteoglycan Content In Fresh And Cryopreserved Porcine Cardiovascular Tissues, Yun Hee Shon
Theses and Dissertations in Biomedical Sciences
The purpose of this research was to study the effects of cryopreservation on the proteoglycan (PG) and mineral content of aorta conduit tissue. Proteoglycans from fresh and cryopreserved porcine aorta conduit tissues were isolated by extraction with 4 M guanidine (Gdn) - hydrochloride (HCl) for 48 hours. Quantitative analysis of extracted proteoglycans revealed that the content of proteoglycan material from cryopreserved tissue, measured as uronate and protein per unit weight of wet tissue, was similar to that from fresh tissue. Gel permeation column chromatography studies suggested that proteoglycans present in three CsCl fractions from cryopreserved tissues had molecular weights similar …
Ribosomal Dna And The Phylogeny Of Frogs, David M. Hills, Loren K. Ammerman, Michael T. Dixon, Rafael O. De Sá
Ribosomal Dna And The Phylogeny Of Frogs, David M. Hills, Loren K. Ammerman, Michael T. Dixon, Rafael O. De Sá
Biology Faculty Publications
Phylogenetic analysis of 1656 aligned sites in the 28S ribosomal RNA gene of frogs supports some of the recently recognized higher groups of anurans but provides counter-support for others. The 28S rDNA data support the monophyly of the recently recognized Pipanura (me- sobatrachians plus neobatrachians), which in turn indicates paraphyly of archaeobatrachians. Me- sobatrachians (pelobatoids plus pipoids), which are either considered paraphyletic or weakly sup- ported as monophyletic in morphological analyses, also receive support as a monophyletic group from the 28S rDNA data. Hyloidea (=Bufonoidea), which is widely recognized but lacks morphological support, receives some molecular support as being monophyletic. …
Chronic Estrogen-Induced Alterations In Adrenocorticotropin And Corticosterone Secretion: Relationship To Mineralocorticoid And Glucocorticoid Receptor Regulation In The Female Rat Anterior Pituitary Gland And Brain, Loyd H. Burgess
Dissertations
No abstract provided.
The Effects Of Teratogens On Serotonin Expression In Drosophila Embryonic Cell Cultures, Keri Joel Hopkins
The Effects Of Teratogens On Serotonin Expression In Drosophila Embryonic Cell Cultures, Keri Joel Hopkins
Theses Digitization Project
No abstract provided.
Characterization Of Early B Lymphocyte Activation During Trichinella Spiralis Infection In Rats, Elizabeth Margaret Richards
Characterization Of Early B Lymphocyte Activation During Trichinella Spiralis Infection In Rats, Elizabeth Margaret Richards
Theses Digitization Project
No abstract provided.
Ultrastructure And Mitosis Of Glaucosphaera Vacuolata, Steven Philip Allan Goss
Ultrastructure And Mitosis Of Glaucosphaera Vacuolata, Steven Philip Allan Goss
Dissertations, Theses, and Masters Projects
No abstract provided.