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Docking Study Of Selected Citrus Flavonoids Towards Exploring The Potential Anti Estrogen Activity, Indira M., Krupanidhi S, Venkateswarulu T.C., Md. Nazneen Bobby, Keerthi P, Satya Kavya P, Amaze M, Abraham Peele K
Docking Study Of Selected Citrus Flavonoids Towards Exploring The Potential Anti Estrogen Activity, Indira M., Krupanidhi S, Venkateswarulu T.C., Md. Nazneen Bobby, Keerthi P, Satya Kavya P, Amaze M, Abraham Peele K
Karbala International Journal of Modern Science
Breast cancer is one of the serious health issues for the women and it has been characterized with uncontrolled growth of cells in the breast tissue. An elevated level of expression of estrogen promotes survival to breast cancerous cells. The present study is focused on phytochemicals, to screen the inhibition of estrogen receptor activity. The selected phytochemicals’ are citrus flavonoids having anti-cancer, anti-oxidative, anti-proliferative, anti-angiogenic, anti-estrogenic and anti-inflammatory activities. The crystal structure of human estrogen receptor with PDB ID: 2IOG are retrieved from protein data bank (PDB) and citrus flavanoids from Pub Chem database. The drug behavior was studied using …