Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Biotechnology

Theses/Dissertations

2019

Power of discrimination

Articles 1 - 2 of 2

Full-Text Articles in Life Sciences

Study Of Insertion-Deletion Polymorphisms (Indels) In The Uae Population, Maryam M. Matar Almheiri Apr 2019

Study Of Insertion-Deletion Polymorphisms (Indels) In The Uae Population, Maryam M. Matar Almheiri

Biology Theses

Insertion-deletion polymorphisms (indels) have been used less in forensic identification of individuals in comparison to short tandem repeat (STR) and single nucleotide polymorphism (SNP) systems. The use of indels has many advantages including low costs, simple typing methods as well as a small amplicon size of under 160 bp making them suitable for genotyping highly degraded DNA. They can also be valuable as a complementary tool to help resolve kinship cases, with the advantage of lower mutation rates when compared to STRs.

The main objective of this study was to investigate the polymorphism of 30 indel loci in the UAE …


Study Of Autosomal Str Markers In United Arab Emirates Population, Mohammed Naji Mohammed Apr 2019

Study Of Autosomal Str Markers In United Arab Emirates Population, Mohammed Naji Mohammed

Biology Theses

A study of the United Arab Emirates (UAE) population is important due to high consanguineous marriage, which may affect the power of discrimination of some loci. The genetic polymorphisms of 23 autosomal short tandem repeat (STR) loci including D3S1358, vWA, D16S539, CSF1PO, TPOX, D8S1179, D21S11, D18S51, D2S441, D19S433, TH01, FGA, D22S1045, D5S818, D13S317, D7S820, D10S1248, D1S1656, D12S391, D2S1338, D6S1043, Penta D and Penta E were evaluated in 571 random unrelated UAE Arabs population. Blood samples were collected on FTA cards. Targeted loci were amplified using Verifiler Express PCR Amplification Kit. PCR products were run on the ABI 3500 Genetic analyzer. …