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Full-Text Articles in Life Sciences
Morphological And Transcriptional Effects Of Crude Oil And Dispersant Exposure On The Marine Sponge Cinachyrella Alloclada, Yvain Desplat, Jacob F. Warner, Emily J. Blake, Nidhi Vijayan, Marie Cuvelier, Patricia Blackwelder, Jose V. Lopez
Morphological And Transcriptional Effects Of Crude Oil And Dispersant Exposure On The Marine Sponge Cinachyrella Alloclada, Yvain Desplat, Jacob F. Warner, Emily J. Blake, Nidhi Vijayan, Marie Cuvelier, Patricia Blackwelder, Jose V. Lopez
Biology Faculty Articles
Marine sponges play important roles in benthic ecosystems. More than providing shelter and food to other species, they help maintain water quality by regulating nitrogen and ammonium levels in the water, and bioaccumulate heavy metals. This system, however, is particularly sensitive to sudden environmental changes including catastrophic pollution event such as oil spills. Hundreds of oil platforms are currently actively extracting oil and gas in the Gulf of Mexico. To test the vulnerability of the benthic ecosystems to oil spills, we utilized the Caribbean reef sponge, Cinachyrella alloclada, as a novel experimental indicator. We have exposed organisms to crude …
Periodic Spatial Disturbances Alter The Expression Of Quorum Sensing Virulence Factors In Pseudomonas Aeruginosa, Laura García-Diéguez
Periodic Spatial Disturbances Alter The Expression Of Quorum Sensing Virulence Factors In Pseudomonas Aeruginosa, Laura García-Diéguez
All HCAS Student Capstones, Theses, and Dissertations
Pseudomonas aeruginosa is an opportunistic pathogen associated with severe acute and chronic illnesses. Current antibiotic-based approaches fail to effectively treat P. aeruginosa infections due to the effectiveness and robustness of the quorum sensing signaling system (QS). Pathogenic bacteria, such as P. aeruginosa, employ this population density-dependent communication mechanism to confer antimicrobial resistance, propagate infection, and coordinate the expression of virulence factors, through the production and detection of autoinducing signaling molecules (AI). As such, there is a growing interest in developing novel non-antibiotic-based techniques to attenuate the pathogenicity of P. aeruginosa by disrupting the functionality of its QS system. Previous …