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Articles 1 - 11 of 11
Full-Text Articles in Life Sciences
Quantifying Life History Energetics Of An Oviparous Elasmobranch Subject To Future Warming Water, Carolyn R. Wheeler
Quantifying Life History Energetics Of An Oviparous Elasmobranch Subject To Future Warming Water, Carolyn R. Wheeler
Graduate Doctoral Dissertations
Marine ectothermic fishes – fishes that do not regulate internal body temperature independent from the water temperature – are some of the most vulnerable organisms to rapid and alarming increases in environmental temperature occurring due to climate change mediated-ocean warming. For tropical fish species that live near their thermal maxima, this warming could be of grave consequence to individuals, populations, and whole marine ecosystems. Certain key life stages such as embryos and reproducing adults may be particularly vulnerable to warming given the excess energetic costs of these life stages, which may disallow compensation for extreme changes in temperature. One taxonomic …
Pollutants Corrupt Resilience Pathways Of Aging In The Nematode C. Elegans, Andrea Scharf, Annette Limke, Karl Heinz Guehrs, Anna Von Mikecz
Pollutants Corrupt Resilience Pathways Of Aging In The Nematode C. Elegans, Andrea Scharf, Annette Limke, Karl Heinz Guehrs, Anna Von Mikecz
Biological Sciences Faculty Research & Creative Works
Delaying aging while prolonging health and lifespan is a major goal in aging research. One promising strategy is to focus on reducing negative interventions such as pollution and their accelerating effect on age-related degeneration and disease. Here, we used the short-lived model organism C. elegans to analyze whether two candidate pollutants corrupt general aging pathways. We show that the emergent pollutant silica nanoparticles (NPs) and the classic xenobiotic inorganic mercury reduce lifespan and cause a premature protein aggregation phenotype. Comparative mass spectrometry revealed that increased insolubility of proteins with important functions in proteostasis is a shared phenotype of intrinsic- and …
Intracellular Hemin Is A Potent Inhibitor Of The Voltage-Gated Potassium Channel Kv10.1, Nirakar Sahoo, Kefan Yang, Alisa Bernert, Sandip M. Swain, Guido Gessner, Reinhard Kappl, Toni Kühl, Diana Imhof, Toshinori Hoshi, Roland Schönherr, Stefan H. Heinemann
Intracellular Hemin Is A Potent Inhibitor Of The Voltage-Gated Potassium Channel Kv10.1, Nirakar Sahoo, Kefan Yang, Alisa Bernert, Sandip M. Swain, Guido Gessner, Reinhard Kappl, Toni Kühl, Diana Imhof, Toshinori Hoshi, Roland Schönherr, Stefan H. Heinemann
Biology Faculty Publications and Presentations
Heme, an iron-protoporphyrin IX complex, is a cofactor bound to various hemoproteins and supports a broad range of functions, such as electron transfer, oxygen transport, signal transduction, and drug metabolism. In recent years, there has been a growing recognition of heme as a non-genomic modulator of ion channel functions. Here, we show that intracellular free heme and hemin modulate human ether à go-go (hEAG1, Kv10.1) voltage-gated potassium channels. Application of hemin to the intracellular side potently inhibits Kv10.1 channels with an IC50 of about 4 nM under ambient and 63 nM under reducing conditions in a weakly voltage-dependent manner, …
Connecting Above- And Belowground Effects Of Climate Warming On Bumble Bee Health, Francis Mullan
Connecting Above- And Belowground Effects Of Climate Warming On Bumble Bee Health, Francis Mullan
Master of Science in Integrative Biology Theses
Climate warming has been identified as one of the primary factors causing worldwide pollinator declines. One of the most at-risk groups of pollinators is bumble bees (Bombus spp.). Bumble bees are common, widespread, and key pollinators of a wide range of crops and wild plants. Although studies have examined the thermal physiological traits of individual bumble bees to understand how they may be impacted by climate warming, little to no studies have examined how climate warming may impact whole bumble bee colonies both in their ability to thermoregulate their nest for their brood or in their ability to forage …
How Are Changes In Temperature And Salinity Impacting Intertidal Mussels?, Casey A. Martin
How Are Changes In Temperature And Salinity Impacting Intertidal Mussels?, Casey A. Martin
Student Research Symposium
Marine organisms living within the intertidal zones, such as mussels, experience a wide range of environmental conditions every day. Due to Climate change, these environments are transforming in such a way that may impact a mussels ability to successfully reproduce, grow, and live. Previous studies have shown that successful gamete development in freshwater mussels has been linked to temperature and species behavior has been observed to be influenced by salinity levels. In order to test the impact of temperature and salinity on mussel physiology, mussels were exposed to several treatments with varying conditions. Those conditions included a combination of a …
The Consequences Of Climate Change For Native Bee Assemblages, Melanie R. Kazenel
The Consequences Of Climate Change For Native Bee Assemblages, Melanie R. Kazenel
Biology ETDs
Recent declines in terrestrial arthropod biodiversity highlight the need to pinpoint which taxa and ecosystem services are most threatened, and why. But, for most of the world’s ~20,000 bee species, we lack robust evidence of population trends, and the role of climate change remains surprisingly little studied. I used long-term bee monitoring data from the Sevilleta Long-Term Ecological Research Program (Socorro, NM, USA), along with complementary experimental and observational data, to examine how climate relates to bee abundance and diversity patterns over time and space, and to identify the traits that govern bees’ climate sensitivities.
From Gene Expression To Physiology: A Study Of Chronic Thermal Tolerance In The Mytilus Edulis Species Complex, Lindsey Cate Schwartz
From Gene Expression To Physiology: A Study Of Chronic Thermal Tolerance In The Mytilus Edulis Species Complex, Lindsey Cate Schwartz
Theses and Dissertations
Rising ocean temperatures are a severe and ever-present threat to marine life. With environmental temperature having such a large impact on organismal performance, understanding the mechanisms which contribute to the ability to survive at higher temperatures is a crucial research focus. Significant progress has been made in discovering these mechanisms on the cellular, biochemical, and physiological levels, but is it much less common for those to be examined together. Using the Mytilus edulisspecies complex as a model system, this dissertation takes a closer look at how prolonged exposure to sub-lethal high temperatures impacts marine organisms on multiple levels of …
Drivers And Direct Impacts Of Lean Mass Dynamics On The Stopover Ecology And Migratory Pace Of Nearctic-Neotropical Migrant Songbirds In Spring, Mariamar Gutierrez Ramirez
Drivers And Direct Impacts Of Lean Mass Dynamics On The Stopover Ecology And Migratory Pace Of Nearctic-Neotropical Migrant Songbirds In Spring, Mariamar Gutierrez Ramirez
Doctoral Dissertations
Annual migration in songbirds is one of the most demanding life-history stages. It represents a period of high mortality, yet there is still much unknown about the ecological correlates that influence its successful completion. After long non-stop migratory flights, birds require a stopover period to rest and replenish depleted energy reserves. Birds use fat as the primary fuel to power long-distance flights. However, birds also burn lean tissue, which results in significant reductions in muscle and organ masses. The discovery and quantification of lean mass catabolism represented a paradigm shift in migration ecology because non-fat components were thought to remain …
Influence Of Temperature On Passage Rate In Sceloporus Consobrinus, With Comparison To Congeners, Allison Litmer
Influence Of Temperature On Passage Rate In Sceloporus Consobrinus, With Comparison To Congeners, Allison Litmer
Arkansas Women in STEM Conference
Variation in energy acquisition, genetics, and environment determine life history traits among individuals, populations, and species. Therefore, influence of climate change may differ by population or even individual. Sceloporus lizards are used as model organisms for thermal biology, and climate modeling. However, it is often assumed that locally-measured thermal and bioenergetic responses apply among broadly similar species, and throughout intraspecific geographic range. The objective of this project was twofold: 1) to quantify the influence of temperature on passage rate in Sceloporus consobrinus from Arkansas, and 2) compare the influence of temperature on passage rate between S. consobrinus, and published …
Relating Metabolic Phenotypes To Movement Behavior In Brook Trout, Jacob E. Bowman
Relating Metabolic Phenotypes To Movement Behavior In Brook Trout, Jacob E. Bowman
All NMU Master's Theses
Brook trout movement-related life history strategies vary considerably and range from individuals that stay within the same 100 meters their entire life to individuals that are potamodromous or anadromous. Potential drivers of movement life histories have been the subject of much research in fish, with genetic subpopulation explanations often failing to explain the phenomenon. Metabolic phenotypes have been suggested as a possible driver for expression of different movement life histories. I investigated if metabolic phenotypes are related to movement strategies within a population of brook trout (Salvelinus fontinalis) in Unnamed Creek, a tributary to the Rock River, Alger …
Beyond Cortisol: Indicators Of Stress And Negative Feedback In Plasma And Blubber Of Marine Mammals, Jessica Avalos
Beyond Cortisol: Indicators Of Stress And Negative Feedback In Plasma And Blubber Of Marine Mammals, Jessica Avalos
University of the Pacific Theses and Dissertations
Marine mammals play an important role in ecosystem stability. However, anthropogenic activity is compounding pressure on many already vulnerable populations. A potential consequence of anthropogenic disturbance is physiological stress, which can impact metabolism, immunity, and reproduction, especially if it occurs repeatedly. Previous studies on marine mammals have focused on acute stress, but the impacts of repeated stress are poorly understood. Due to its accessibility on land during haul-outs, the northern elephant seal (Mirounga angustirostris) is a good system in which to study the effects of stress in marine mammals. Stress stimulates the release of glucocorticoid hormones, primarily cortisol. Elevated cortisol …