Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- African green monkey (1)
- Anterior segment (1)
- Attention (1)
- Basement membrane (1)
- Behavioral Ecology (1)
-
- Bmp5 (1)
- Col1a1 (1)
- Coloboma (1)
- Comparative transcriptomics (1)
- EEG (1)
- Evolutionary Ecology (1)
- Eye development (1)
- F-actin (1)
- Foxc1 (1)
- Hyaloid vasculature (1)
- Hypertension (1)
- Mean phase coherence (1)
- Meditation (1)
- Neodiprion (1)
- Neural dynamics (1)
- Nonhuman primates (1)
- Optic fissure fusion (1)
- Pax2 (1)
- Performance (1)
- Periocular mesenchyme (1)
- Pitx2 (1)
- Postpartum hypertension (1)
- Preeclampsia (1)
- Puerperial hypertension (1)
- Regeneration (1)
Articles 1 - 7 of 7
Full-Text Articles in Life Sciences
Impact Of Short Meditation On Attentional Performance, Lauren E. Guerriero
Impact Of Short Meditation On Attentional Performance, Lauren E. Guerriero
Theses and Dissertations--Biology
Meditation describes a large variety of traditions that all include the conscious focus of attention. By maintaining attention, meditators experience both acute and long-term changes in physiology, anatomy, and cognitive performance. The type of performance benefit is believed to depend, at least in part, on the specific type of mental training. What is much less clear in the literature is the impact of a single session of meditation on the brain and how the acute changes could impact performance. Studies in advanced meditators show an increase in neuronal coordination and slowing of neuronal firing across many regions in the brain, …
Molecular Mechanisms Regulating Optic Fissure Fusion During Zebrafish Eye Development, Megan Weaver
Molecular Mechanisms Regulating Optic Fissure Fusion During Zebrafish Eye Development, Megan Weaver
Theses and Dissertations--Biology
Vertebrate retinal development requires timely and precise fusion of the optic fissure. Failure of this event leads to congenital vision impairment in the form of coloboma. Recent studies have suggested hyaloid vasculature to be involved in OF fusion. In order to examine this link, we analyzed optic fissure fusion and hyaloid vasculogenesis in the zebrafish pax2a noi mutant line. We first determined that pax2a-/- embryos fail to accumulate F-actin in the optic fissure prior to basement membrane (BM) degradation. Furthermore, using 3D and live imaging we observed reduced OF hyaloid vascularization in pax2a-/- embryos. When examining the connection …
Spontaneous Postpartum Hypertension In The African Green Monkey, Patrick Rivera
Spontaneous Postpartum Hypertension In The African Green Monkey, Patrick Rivera
Theses and Dissertations--Biology
Postpartum hypertension (PPHT) is a hypertensive disorder of the puerperium that occurs in women at a rate between 0.8-28% although the exact incidence is unknown due primarily to its transient presentation during a time of reduced medical supervision. The etiology of PPHT is currently unknown with no present experimental animal model. We present the African green monkey (Chlorocebus aethiops sabaeus; AGM) as a potentially translational NHP model of PPHT in humans. AGMs were identified as PPHT using Doppler sphygmomanometry and American Heart Association standards of hypertension for systolic blood pressure (systolic blood pressure > 140 mmHg). Disease characteristics were …
Leveraging Transcriptomic Approaches To Identify Differences In Genetic Programming Driving Two Distinct Wound Healing Mechanisms, Regeneration And Fibrosis, In Acomys And Mus, Shishir K. Biswas
Theses and Dissertations--Biology
Why can some animals and others cannot? This fundamental question has fueled scientists studying regeneration for hundreds of years since early observations in crayfish, salamanders and many other organisms. While most contemporary work in regeneration is done in a handful of species including salamanders, zebrafish and flatforms, these organisms lack a closely-related, non-regenerating sister species from which unique genetic differences can be identified. Additionally, while much has been learned from these organisms, they do not share fundamental biological traits with mammals (endothermy, metabolism and immune system) which limits the ability to translate this research for clinical medicine. To this end, …
Characterization Of Spontaneous Preeclampsia In The African Green Monkey (Chlorocebus Aethiops Sabaeus), Chelsea Christina Weaver
Characterization Of Spontaneous Preeclampsia In The African Green Monkey (Chlorocebus Aethiops Sabaeus), Chelsea Christina Weaver
Theses and Dissertations--Biology
Hypertensive pregnancy disorders are a major contribution to maternal and neonatal mortality worldwide. Two of these disorders, preeclampsia and chronic hypertension in pregnancy, affect up to 10% of all pregnancies. These hypertensive disorders of pregnancy are associated with long-term, postnatal risk factors for both mother and offspring. Despite numerous recent advances in preeclampsia research, the underlying mechanisms are still not understood. This could be due to lack of a spontaneous animal model. This dissertation presents the African Green Monkey (AGM; Chlorocebus aethiops sabaeus) as the first known spontaneous animal model of preeclampsia and a highly translational model of chronic …
The Social Behavior Of Pine Sawflies In The Genus Neodiprion, John W. Terbot Ii
The Social Behavior Of Pine Sawflies In The Genus Neodiprion, John W. Terbot Ii
Theses and Dissertations--Biology
Group living is found across the animal kingdom ranging from temporary mating aggregations to complex, eusocial lifestyles. A particularly common form of group living found among insects are larval or nymphal herds. This lifestyle consists of immature insects living together and results in several proposed costs and benefits. Benefits of this lifestyle include improved ability to regulate a group’s microenvironment, more efficient use of their host, and the ability to engage in collective predator defenses. Offsetting these benefits are costs resulting from living in close proximity to conspecifics which include increased competition, greater visibility to predators, and heightened disease risks. …
Periocular Mesenchyme Heterogeneity During Morphogenesis Of The Vertebrate Ocular Anterior Segment, Kristyn L. Van Der Meulen
Periocular Mesenchyme Heterogeneity During Morphogenesis Of The Vertebrate Ocular Anterior Segment, Kristyn L. Van Der Meulen
Theses and Dissertations--Biology
The vertebrate eye is a complex organ, responsible for the primary sense with which we interact with our environment: vision. Development of the eye is a tightly regulated process, controlled by a vast network of genes. This process begins with eye morphogenesis, when the eye structure is formed through a series of morphogenetic movements and culminates in the creation of the optic cup, lens, and presumptive optic stalk. Next, retinal differentiation creates the critical cell layers of the retina needed to process light waves that enter the eye, including rod and cone photoreceptors, interneurons, and support cells. Failure in either …