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Full-Text Articles in Life Sciences
Epigenetics As Driver Of Adaptation And Diversification In Microbial Eukaryotes, Agnes K.M. Weiner, Laura A. Katz
Epigenetics As Driver Of Adaptation And Diversification In Microbial Eukaryotes, Agnes K.M. Weiner, Laura A. Katz
Biological Sciences: Faculty Publications
No abstract provided.
Opinion: Genetic Conflict With Mobile Elements Drives Eukaryotic Genome Evolution, And Perhaps Also Eukaryogenesis, Adena B. Collens, Laura A. Katz
Opinion: Genetic Conflict With Mobile Elements Drives Eukaryotic Genome Evolution, And Perhaps Also Eukaryogenesis, Adena B. Collens, Laura A. Katz
Biological Sciences: Faculty Publications
Through analyses of diverse microeukaryotes, we have previously argued that eukaryotic genomes are dynamic systems that rely on epigenetic mechanisms to distinguish germline (i.e., DNA to be inherited) from soma (i.e., DNA that undergoes polyploidization, genome rearrangement, etc.), even in the context of a single nucleus. Here, we extend these arguments by including two well-documented observations: (1) eukaryotic genomes interact frequently with mobile genetic elements (MGEs) like viruses and transposable elements (TEs), creating genetic conflict, and (2) epigenetic mechanisms regulate MGEs. Synthesis of these ideas leads to the hypothesis that genetic conflict with MGEs contributed to the evolution of a …