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Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Biology

2021

Portland State University

Microorganisms -- Genetic aspects

Articles 1 - 2 of 2

Full-Text Articles in Life Sciences

Complete Mitochondrial Genome Sequence Of The Gulf Coast Tick (Amblyomma Maculatum), Amanda E. Brenner, Rahul Raghavan Sep 2021

Complete Mitochondrial Genome Sequence Of The Gulf Coast Tick (Amblyomma Maculatum), Amanda E. Brenner, Rahul Raghavan

Biology Faculty Publications and Presentations

The complete circularized mitochondrial genome sequence of Amblyomma maculatum is 14,803 bp long. It encodes 13 protein coding genes, 2 rRNA genes, 22 tRNA genes, 2 tick box motifs, and 2 control regions. The gene arrangement and content are consistent with those of previously reported Metastriata tick mitochondrial genomes.


Male Fetal Sex Affects Uteroplacental Angiogenesis In Growth Restriction Mouse Model, Jessica F. Hebert, Jess A. Millar, Rahul Raghavan, Amie L. Romney, Jason Podrabsky, Monique Y. Rennie, Allison Felker, Perrie O'Tierney-Ginn, Mayu Morita, Elizabeth A. Dupriest, Terry K. Morgan Jan 2021

Male Fetal Sex Affects Uteroplacental Angiogenesis In Growth Restriction Mouse Model, Jessica F. Hebert, Jess A. Millar, Rahul Raghavan, Amie L. Romney, Jason Podrabsky, Monique Y. Rennie, Allison Felker, Perrie O'Tierney-Ginn, Mayu Morita, Elizabeth A. Dupriest, Terry K. Morgan

Biology Faculty Publications and Presentations

Abnormally increased angiotensin II activity related to maternal angiotensinogen (AGT) genetic variants, or aberrant receptor activation, is associated with small-for-gestational-age (SGA) babies and abnormal uterine spiral artery remodeling in humans. Our group studies a murine AGT gene titration transgenic (TG; 3-copies of the AGT gene) model, which has a 20% increase in AGT expression mimicking a common human AGT genetic variant (A[-6]G) associated with intrauterine growth restriction (IUGR) and spiral artery pathology. We hypothesized that aberrant maternal AGT expression impacts pregnancy-induced uterine spiral artery angiogenesis in this mouse model leading to IUGR. We controlled for fetal sex and fetal genotype …