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Biology

1969

Cholesterol

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A Study Of The Effects Of Sitosterol Ingestion On The Serum Cholesterol Concentrations Of Two Genetically Different Strains Of Laboratory Mice, Marie Nichols Goldberg Jan 1969

A Study Of The Effects Of Sitosterol Ingestion On The Serum Cholesterol Concentrations Of Two Genetically Different Strains Of Laboratory Mice, Marie Nichols Goldberg

University of the Pacific Theses and Dissertations

A possible interrelationship between serum cholesterol level and atherosclerosis has long interested investigators in the fields of physiology and biochemistry. Cholesterol is found in very high concentrations in the plaques that occlude coronary arteries in man and laboratory animals. It is generally agreed that hypercholesterolemia favors the appearance of atherosclerotic lesions.1<1

In recent years, much information has been accumulated regarding the factors which affect the serum cholesterol level. Exact and detailed biochemical mechanisms are still not clearly understood. However, it has been demonstrated that the serum cholesterol levels of man and several experimental animals can be lowered significantly by …