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Full-Text Articles in Life Sciences
Toxic Effect Of Lead Chloride On Antioxidant Enzyme In The Liver And Kidney Of Fish, Bakhtawar Raza, Muhammad Javed, Faiza Ambreen, Fariha Latif
Toxic Effect Of Lead Chloride On Antioxidant Enzyme In The Liver And Kidney Of Fish, Bakhtawar Raza, Muhammad Javed, Faiza Ambreen, Fariha Latif
Journal of Bioresource Management
The contamination of aquatic habitats has become a serious problem for sustainability of the fisheries sector in Pakistan. Among different pollutants, heavy metals are very toxic. Their toxicity can be assessed by using antioxidant enzymes as biomarkers. These enzymes protect the living organisms from the oxidative stress caused by the heavy metals. Therefore, the effect of lead chloride (PbCl2) on the peroxidase enzyme activity in the tissues (liver and kidney) of Cirrhinamrigala was investigated. Four groups of Cirrhinamrigala were exposed, separately, to 96-hr LC50 concentration of PbCl2 along with its sub-lethal concentrations, viz.2/3rd, 1/4th and 1/5th for a period of …
Metal Mixtures Toxicity And Bioaccumulation In Tilapia Nilotica At 96-Hr Lc50 Exposure, Faiza Ambreen, Muhammad Javed
Metal Mixtures Toxicity And Bioaccumulation In Tilapia Nilotica At 96-Hr Lc50 Exposure, Faiza Ambreen, Muhammad Javed
Journal of Bioresource Management
Laboratory tests were conducted on fingerlings of Tilapia nilotica to check the bioaccumulation patterns of lead (Pb), cadmium (Cd) and cobalt (Co) during acute toxicity at constant water temperature, pH and total hardness. Metal mixtures viz. Lead + Cadmium, Cobalt-Lead and Cadmium-Cobalt were selected to assess the acute toxicity in terms of 96-hr LC50 along with bioaccumulation patterns in selected organs of Tilapia nilotica (skin, muscles and liver). Sensitivity of Tilapia nilotica in terms of 96-hr LC50 for all mixtures varied significantly. The 96-hr LC50 of binary metal mixtures agreed in that order: cadmium-cobalt > lead-cadmium > cobalt-lead with statistically significant differences …
High Dietary Fructose Load Aggravates Lipid Metabolism In The Liver Of Wistar Rats Through Imbalance Between Lipogenesis And Fatty Acid Oxidation, Ana Teofilovic, Biljana Bursac, Ana Djordjevic, Danijela Vojnovic Milutinovic, Gordana Matic, Natasa Velickovic
High Dietary Fructose Load Aggravates Lipid Metabolism In The Liver Of Wistar Rats Through Imbalance Between Lipogenesis And Fatty Acid Oxidation, Ana Teofilovic, Biljana Bursac, Ana Djordjevic, Danijela Vojnovic Milutinovic, Gordana Matic, Natasa Velickovic
Turkish Journal of Biology
Fructose ingestion is often associated with hepatic steatosis and hypertriglyceridemia. The homeostasis of hepatic lipids is mainly determined by the interplay of lipogenesis and fatty acid β-oxidation. In this study, we hypothesized that high fructose intake disturbs hepatic lipid metabolism through an imbalance between these processes. Therefore, we analyzed the effects of a 9-week-long consumption of a 60% fructose solution on physiological parameters, glycemia, and blood lipid profiles in male Wistar rats. The expression of key regulators of fatty acid oxidation (FAO) and lipogenesis in the liver were assessed by western blot and quantitative polymerase chain reaction. The results showed …
Histopathological And Biochemical Changes In The Liver, Kidney, And Bloodof Amphibians Intoxicated With Cadmium, Marcela Fátima Medina, Maria Elina González, Sandra Maria Roxana Klyver, Iris Maria Aybar Odstrcil
Histopathological And Biochemical Changes In The Liver, Kidney, And Bloodof Amphibians Intoxicated With Cadmium, Marcela Fátima Medina, Maria Elina González, Sandra Maria Roxana Klyver, Iris Maria Aybar Odstrcil
Turkish Journal of Biology
The worldwide decline in amphibian populations has made heavy metal pollution a subject of interest. The aim of this work was to analyze the effect of sublethal doses of cadmium (Cd) on the liver, kidney, and blood of Rhinella arenarum specimens. Serum markers indicative of hepatic injury (gamma glutamyltransferase, alkaline phosphatase, pseudo cholinesterase, and total cholesterol) and markers of renal dysfunction (blood urea nitrogen, serum creatinine, calcium, and glucose) showed variation in animals treated with a 0.5 mg/kg dose compared to controls. Histopathological images revealed alterations in the liver (hepatocyte ballooning and hyperplasia of Kupffer cells) and kidney (renal tubular …