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Determination Of Mutagenic Potencies Of Aqueous Extracts Of Thermopsis Turcica By Ames Test, Recep Li̇man, Yasi̇n Eren, Di̇lek Akyil, Muhsi̇n Konuk
Determination Of Mutagenic Potencies Of Aqueous Extracts Of Thermopsis Turcica By Ames Test, Recep Li̇man, Yasi̇n Eren, Di̇lek Akyil, Muhsi̇n Konuk
Turkish Journal of Biology
Thermopsis turcica is an endemic species of Turkey popularly known as Eber Sarısı or Piyam; it is a member of the Thermopsis genus, which contains plants considered to be medicinal throughout the world. In this study, the mutagenic effect of aqueous extracts obtained from the leaves, root, stem, and flowers of T. turcica were evaluated by the Ames test, using Salmonella typhimurium TA97, TA98, TA100, and TA102 strains with and without an S9 activation system. The results obtained were analyzed statistically using SPSS for Windows, and the Mann-Whitney test was performed for comparisons. The results showed that all of the …
Genotoxic And Mutagenic Effects Of Aqueous Extract From Aerial Parts Of Achillea Teretifolia, Di̇lek Akyil, Sedat Oktay, Recep Li̇man, Yasi̇n Eren, Muhsi̇n Konuk
Genotoxic And Mutagenic Effects Of Aqueous Extract From Aerial Parts Of Achillea Teretifolia, Di̇lek Akyil, Sedat Oktay, Recep Li̇man, Yasi̇n Eren, Muhsi̇n Konuk
Turkish Journal of Biology
Genotoxic and mutagenic effects of aqueous extract from aerial parts of Achillea teretifolia (At-ext) were investigated using both Allium cepa root meristematic cells and a short-term mutation assay in Salmonella typhimurium with TA98 and TA100 strains in the presence or absence of S9 mix, respectively. In the Allium tests, EC_{50} value was determined as 50 g/L, and 0.5 × EC_{50}, EC_{50}, and 2 × EC_{50} concentrations of At-ext were applied to onion tuber roots. Methyl methane sulfonate (MMS, 10 ppm) and distilled water were used as positive and negative controls, respectively. The mitotic index (MI) increased in all concentrations in …