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Determination Of Mutagenic Potencies Of Aqueous Extracts Of Thermopsis Turcica By Ames Test, Recep Li̇man, Yasi̇n Eren, Di̇lek Akyil, Muhsi̇n Konuk
Determination Of Mutagenic Potencies Of Aqueous Extracts Of Thermopsis Turcica By Ames Test, Recep Li̇man, Yasi̇n Eren, Di̇lek Akyil, Muhsi̇n Konuk
Turkish Journal of Biology
Thermopsis turcica is an endemic species of Turkey popularly known as Eber Sarısı or Piyam; it is a member of the Thermopsis genus, which contains plants considered to be medicinal throughout the world. In this study, the mutagenic effect of aqueous extracts obtained from the leaves, root, stem, and flowers of T. turcica were evaluated by the Ames test, using Salmonella typhimurium TA97, TA98, TA100, and TA102 strains with and without an S9 activation system. The results obtained were analyzed statistically using SPSS for Windows, and the Mann-Whitney test was performed for comparisons. The results showed that all of the …
Genotoxicity Of Bovine Bone-Derived Microhydroxyapatite (Boneplus-Xs), Mehmet Topaktaş, Erman Sali̇h İsti̇fli̇, Mehmet Büyükleyla, Hasan Basri̇ İla, Tuba Canitezer, Mehmet Kürkçü
Genotoxicity Of Bovine Bone-Derived Microhydroxyapatite (Boneplus-Xs), Mehmet Topaktaş, Erman Sali̇h İsti̇fli̇, Mehmet Büyükleyla, Hasan Basri̇ İla, Tuba Canitezer, Mehmet Kürkçü
Turkish Journal of Biology
The aim of this study was to evaluate the genotoxic effect of a bovine bone-derived hydroxyapatite (HA), Boneplus-xs (B-P-XS). The genotoxicity of B-P-XS was investigated by examining the potential of the xenograft (B-P-XS) to induce gene mutation (evaluated using the Ames test), in vitro chromosome aberration (CA), and sister chromatid exchange (SCE) with tests in cultured human peripheral lymphocytes. Counts of reverse mutations in Salmonella typhimurium TA98 and TA100 strains were not found to be significantly increased after treatment with B-P-XS (P > 0.05). The presence of B-P-XS in peripheral blood culture for 24 and 48 h did not lead to …