Life Sciences Commons^™

Clinical Applications Of Electron Microscopy In The Analysis Of Collagenous Biomaterials, Arthur J. Wasserman, Charles J. Doillon, Alvin I. Glasgold, Y. Pedro Kato, David Christiansen, Azam Rizvi, Eric Wong, Jack Goldstein, Frederick H. Silver

Scanning Microscopy

Scanning and transmission electron microscopy are of clinical value in assessing the interaction between biomaterials and ingrowing tissues. Ultrastructural information allows the clinician and biomaterials specialist to determine events occurring during wound healing and the biocompatibility of prosthetic devices. This paper reviews some of the experimental and clinical studies done in our laboratory on the use of natural and reconstituted collagen as replacements for connective tissues. Consideration is given to collagen flakes used for the treatment of dermal ulcers, a collagen fiber prosthesis used for tendon and ligament replacement, the effects of chemical preservatives on cartilage used for replacement of …

Scanning Electron Microscope And Intragingival Microorganisms In Periodontal Diseases, F. R. Saglie

Scanning Microscopy

During the past two decades there has been an increased understanding of bacterial invasion as a pathogenic mechanism of periodontal diseases. Scanning Electron Microscope (SEM) has played a key role in supporting the idea that bacterial invasion may be another pathogenic mechanism in periodontal disease. This has been due to the fact that SEM has a larger depth of focus and better resolving power than the Light Microscope (LM) and also allows for observation of rather large areas of tissue showing in depth the surface of the sample.

This review deals with information obtained by using SEM as the fundamental …