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Full-Text Articles in Life Sciences
The Use Of Aloe-Based Silver Nanoparticles As A Possible Treatment For Contaminated Water, Lozetta Davis
The Use Of Aloe-Based Silver Nanoparticles As A Possible Treatment For Contaminated Water, Lozetta Davis
Scholar Week 2016 - present
Water contamination is a world-wide issue that causes the death of millions yearly. This comes from regularly tainted water with water borne pathogens, which is typically seen in undeveloped areas. As antibiotics are used more, more resistance is being seen, and thus newer methods of microbial contamination need to be developed. Silver nanoparticles have shown success in microbial contamination on petri dishes, but not in a water system. It was hypothesized that if silver nanoparticles were added to bacteria contaminated water they would be able to reduce the amount of bacteria present. Silver nanoparticles that are synthesized from plants such …
Total Synthesis And Biological Evaluation Of Siderophores: Key To Develop Iron Chelators And Tackle Antibiotic Delivery To Gram-Negative Bacteria, .Pratibha Desman
Total Synthesis And Biological Evaluation Of Siderophores: Key To Develop Iron Chelators And Tackle Antibiotic Delivery To Gram-Negative Bacteria, .Pratibha Desman
Research Symposium
Siderophores are molecules that act as iron carriers in bacteria. As they sequester iron from the environment and penetrate bacterial cells through active transporters, they can bypass the porin-mediated transportation in Gram-negative bacteria. Therefore, conjugating antibiotics that lacks the ability to pass through porins to siderophores and forming “sideromycins” has been proven as a way to battle antibiotic resistance in Gram-negative bacteria. My research will focus on synthesizing two siderophores, catenulobactin B and talarazine A as well as their analogs and exploring their potential to synthesize sideromycins. These molecules will be synthesized in a modular way and their cytotoxicity, ability …