Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Life Sciences
In-Vitro Analysis Of Potential Autophagy Mediated Safranal-Sorafenib Combined Effect On Hepatocellular Carcinoma, Aaminah Farrukh
In-Vitro Analysis Of Potential Autophagy Mediated Safranal-Sorafenib Combined Effect On Hepatocellular Carcinoma, Aaminah Farrukh
Theses
Hepatocellular carcinoma (HCC) is one of the most commonly occurring cancers worldwide. The risk factors include obesity, hepatitis, alcoholism, smoking etc. One of the biggest associated challenges is the current treatment strategies. The therapeutic options are limited with economical and accessibility challenges, especially with increased HCC incidence. Sorafenib, a multikinase inhibitor, is one of the first FDA approved drugs for HCC. But drug resistance and cancer relapse are a common drawback for this treatment. The need for better treatment is crucial now more than ever. The use of saffron as a potential natural therapeutic option is not a novel strategy. …