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Modulation Of Apoptosis In Breast Cancer Cells Mda-Mb-157, 93a And 93b By Aqueous Extract Of Chinese Medical Herb Scutellaria Barbata, Nathaly Manrique
Modulation Of Apoptosis In Breast Cancer Cells Mda-Mb-157, 93a And 93b By Aqueous Extract Of Chinese Medical Herb Scutellaria Barbata, Nathaly Manrique
Honors Theses
Scutellaria barbata (S. barbata), a Chinese herb used in Traditional Chinese Medicine has been known to contain anti-cancer properties. SB has been investigated as a potential treatment for multiple types of cancer including colon cancer, glioblastoma, and ovarian cancer. Breast cancer cell lines MDA-MB-157 and its APC-mutants 93A and 93B are more resistant to treatment due to genetic modifications. In this study, the effectiveness of S. barbata in apoptotic modulation of breast cancer cell lines MDA-MB-157, 93A, and 93B was investigated. Assessments were performed using green/red/blue fluorescent Apoptosis/Necrosis Detection Kit and the Human Apoptosis Antibody Array - Membrane (43 Targets) …