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Full-Text Articles in Life Sciences
Molecular Analysis Of Arabidopsis Thaliana Genes Involved In Stress Response, Jessica M. Whitlock
Molecular Analysis Of Arabidopsis Thaliana Genes Involved In Stress Response, Jessica M. Whitlock
Honors Capstone Projects - All
Arabidopsis thaliana is an excellent model plant to study various plant processes, including plant’s response to environment, its interactions with other organisms, etc. In this study I characterized eight Arabidopsis genes that are likely to regulate plant’s responses to biotic and abiotic stresses. Microarray analysis was done previously in our lab to identify Arabidopsis genes that are differentially expressed in response to various biotic and abiotic stresses and several plant hormones. The biotic stresses include bacterial, fungal and viral pathogens (both virulent and avirulent strains), sucking and chewing insects. The abiotic stresses include chemicals that induce variety of oxidative stresses …
Root Production And Herbivory In An Upland Grassland Community In Yellowstone National Park, Anna M. Stewart
Root Production And Herbivory In An Upland Grassland Community In Yellowstone National Park, Anna M. Stewart
Honors Capstone Projects - All
Few investigations have been conducted on belowground plant consumption and production due to the difficulty of examining root systems over time without significant disturbance. In most field studies, roots are sampled monthly, a time interval that cannot capture the rapid growth and death of fine roots. The purpose of this study was to estimate rates of root production (growth) and consumption in an upland grassland inYellowstoneNational Park. Root lengths were digitized in four minirhizotron tubes, four times per month (at three-day intervals over ten days) from May - September 2005. I attributed root length that disappeared over each three-day period …
Clonogenicity Of Human Promyelocytic Leukemia Cells Enlarged And Multinucleated By Treatment With Cytochalasin B And Their Potential As Targets For Improved Chemical And Physical Therapeutic Approaches, Shannon Dubois
Honors Capstone Projects - All
Cytochalasin B (CB) is a pharmacological agent produced by fungi that disrupts the actin microfilament cytoskeleton and inhibits cytokinesis. It interferes with the formation of the contractile ring and with the development of the cleavage furrow, thus preventing cell division. When normal cells are treated with CB, cell cycle arrest occurs. However, when neoplastic cells are treated with CB, the cells continue to enter the cell cycle and to make new nuclei, but since cytokinesis cannot occur, the neoplastic cells become enlarged and multinucleated. Our lab proposes that enlarged multinucleated neoplastic cells might be more susceptible to agents damaging DNA …
The Role Of Estrogen Receptor Beta In Neonatal Oocyte Development, Kelsey E. Breen
The Role Of Estrogen Receptor Beta In Neonatal Oocyte Development, Kelsey E. Breen
Honors Capstone Projects - All
Establishment of the pool of primordial follicles is essential for reproduction. Shortly after their formation, female germ cells undergo a series of incomplete cell divisions resulting in clusters called cysts. After birth, mouse germ cell cysts break down into individual oocytes (a process referred to as cyst breakdown) that are surrounded by somatic pre-granulosa cells to form primordial follicles. During the process of cyst breakdown, a subset of oocytes in each cyst dies with only a third of the initial number of oocytes surviving. The mechanisms controlling cyst breakdown and programmed cell death are unknown. Previous studies have focused on …
Genetic Analysis Of Germline Development In The Model Organism C. Elegans, Kaitlyn A. Wurz
Genetic Analysis Of Germline Development In The Model Organism C. Elegans, Kaitlyn A. Wurz
Honors Capstone Projects - All
My research investigated the relationships among several transcriptional and/or post-transcriptional regulators in the C. elegans germ line. I examined the relationship between the rha-1 gene and three other regulatory genes, ego-1, glp-1 and csr-1. These genes function in germline proliferation and differentiation and are required for fertility. Because these genes regulate similar processes, we have investigated the relationships among them. The rha-1 gene encodes an RNA helicase that is required for germline development, chromatin regulation, and RNA interference (RNAi). The ego-1 gene encodes an RNA-directed RNA polymerase that is also required for these processes. Although many of the rha-1 and …