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Biology

Applications and Applied Mathematics: An International Journal (AAM)

Journal

2021

Lyapunov function

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Full-Text Articles in Life Sciences

(R1468) Global Analysis Of An Seirs Model For Covid-19 Capturing Saturated Incidence With Treatment Response, David A. Oluyori, Helen O. Adebayo, Ángel G.C. Pérez Dec 2021

(R1468) Global Analysis Of An Seirs Model For Covid-19 Capturing Saturated Incidence With Treatment Response, David A. Oluyori, Helen O. Adebayo, Ángel G.C. Pérez

Applications and Applied Mathematics: An International Journal (AAM)

In this work, a new SEIRS model with saturated incidence rate and piecewise linear treatment response is proposed to describe the dynamics of COVID-19. It is assumed that the treatment response is proportional to the number of infected people as long as the incidence cases are within the capacity of the healthcare system, after which the value becomes constant, when the number of confirmed cases exceeds the carrying capacity of the available medical facilities. Thus, the basic reproduction number of the model is obtained. It is proved that the disease-free equilibrium is globally asymptotically stable when the basic reproduction number …


Global Stability Of Generalized Within-Host Chikungunya Virus Dynamics Models, Taofeek O. Alade, Afeez Abidemi, Cemil Tunç, Shafeek A. Ghaleb Jun 2021

Global Stability Of Generalized Within-Host Chikungunya Virus Dynamics Models, Taofeek O. Alade, Afeez Abidemi, Cemil Tunç, Shafeek A. Ghaleb

Applications and Applied Mathematics: An International Journal (AAM)

This paper proposes two models of a general nonlinear within-host Chikungunya virus (CHIKV) dynamics. The production, incidence, proliferation and removal rates of all compartments are modeled by general nonlinear functions that satisfy a set of reasonable conditions. The second model takes into consideration two forms of infected host cells: (i) latently infected cells which do not produce the CHIKV, (ii) actively infected cells which generate the CHIKV particles. We show that all the solutions of the models are nonnegative and bounded. The global stability of the steady states of the models is proven by applying Lyapunov method and LaSalle’s invariance …