Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Life Sciences
(R1488) Transformation Of Glucokinase Under Variable Rate Constants And Thermal Conditions: A Mathematical Model, Mukhtar Ahmad Khanday, Roohi Bhat
(R1488) Transformation Of Glucokinase Under Variable Rate Constants And Thermal Conditions: A Mathematical Model, Mukhtar Ahmad Khanday, Roohi Bhat
Applications and Applied Mathematics: An International Journal (AAM)
The glucokinase (GK) in cells plays a pivotal role in the regulation of carbohydrate metabolism and acts as a sensor of glucose. It helps us to control glucose levels during fast and food intake conditions through triggering shifts in metabolism or cell functions. Various forms of hypoglycaemia and hyperglycaemia occur due to the transformations of the gene of the Glucokinase. The mathematical modelling of enzyme dynamics is an emerging research area to serve its role in biological investigations. Thus, it is imperative to establish a mathematical model to understand the kinetics of native and denatured forms of enzyme-GK under thermal …