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Full-Text Articles in Life Sciences
Interaction Of The Human Serine Protease Inhibitor Alpha-1-Antitrypsin With Cryptosporidium Parvum, John Russell Forney
Interaction Of The Human Serine Protease Inhibitor Alpha-1-Antitrypsin With Cryptosporidium Parvum, John Russell Forney
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
The human serine protease inhibitor (serpin) alpha-1-antitrypsin (AAT) was studied for potential interaction with components of the protozoan parasite Cryptosporidium parvum. A homogenate prepared from C. parvum oocysts was incubated with purified human AAT, and complexes formed between the serpin and components of the homogenate were detected using an enzyme-linked immunosorbent assay (ELISA). Serpin:parasite infections were effectively blocked by preincubating AAT with a cognate target enzyme, porcine pancreatic elastase, prior to performing the ELISA on the homogenate. Incubation of a mixture of C. parvum oocysts and sporozoites with AAT demonstrated preferential fluorescence labeling of the sporozoite surface membrane by indirect …
The Role Of Cold Acclimatization On The Biogeography Of The Mountain Chickadee (Parus Gambeli) And The Juniper Titmouse (Parus Ridgwayi), Sheldon J. Cooper
The Role Of Cold Acclimatization On The Biogeography Of The Mountain Chickadee (Parus Gambeli) And The Juniper Titmouse (Parus Ridgwayi), Sheldon J. Cooper
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Biogeographic patterns of animals are shaped by biotic interactions, such as competition, and by abiotic factors, such as climate. Mountain Chickadees (Parus gambeli) and Juniper Titmice (Parus ridgway) are permanent residents of regions of western North America and are ecologically similar, but have different northern range limits. l measured several physiological variables, including basal metabolic rate (BMR), peak metabolic rate (PMR = maximal thermogenic capacity), metabolic response to varying environmental temperature (MRT), evaporative water loss (EWL), and daily energy expenditure (DEE) for summer-and winter-acclimatized Mountain Chickadees and Juniper Titmice to determine if seasonal and interspecific variation in cold tolerance and …
Evolutionary Genetics Of Canyon Treefrogs (Hyla Arenicolor), Roy A. Murray
Evolutionary Genetics Of Canyon Treefrogs (Hyla Arenicolor), Roy A. Murray
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Population genetics is the study of the mechanisms that cause genetic change in populations over time. Genetic changes may lead to both adaptive evolution and speciation. While the former process is fairly well understood, many questions remain unanswered with regard to the process of speciation. How important is population isolation in the process of speciation? How long must populations be isolated before speciation is complete? Are the genetic changes that take place during speciation caused mainly by natural selection or does genetic drift play a substantial role? Can genetic drift alone lead to reproductive isolation? These types of questions have …