Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Life Sciences
Selective Feeding On Nutrient-Rich Particles By Gizzard Shad Dorosoma Cepedianum Does Not Involve Mechanical Sorting, M. K. Heidman, L. L. Holley, Randolph Chambers, S. Laurie Sanderson
Selective Feeding On Nutrient-Rich Particles By Gizzard Shad Dorosoma Cepedianum Does Not Involve Mechanical Sorting, M. K. Heidman, L. L. Holley, Randolph Chambers, S. Laurie Sanderson
Arts & Sciences Articles
Previous field and laboratory studies have concluded that suspension-feeding detritivorous fish such as gizzard shad Dorosoma cepedianum selectively ingest nutrient-rich particles using either mechanical sorting within the oropharyngeal cavity or behavioral selectivity within the environment, but none have distinguished between these hypothesized selection mechanisms. To determine whether mechanical selectivity occurs within the oropharyngeal cavity, gizzard shad were fed particles of standardized size but different carbon and nitrogen content in homogeneous particle suspensions vs. non-homogeneous particle distributions. By comparing foregut and epibranchial organ contents with the particles available in a homogeneous suspension, we demonstrated that the fish did not use mechanical …
Multiple Novel Signals Mediate Thyroid Hormone Receptor Nuclear Import And Export, Manohara S. Mavinakere, Jeremy M. Powers, Kelly S. Subramanian, Vincent R. Roggero, Lizabeth A. Allison
Multiple Novel Signals Mediate Thyroid Hormone Receptor Nuclear Import And Export, Manohara S. Mavinakere, Jeremy M. Powers, Kelly S. Subramanian, Vincent R. Roggero, Lizabeth A. Allison
Arts & Sciences Articles
Thyroid hormone receptor (TR) is a member of the nuclear receptor superfamily that shuttles between the cytosol and nucleus. The fine balance between nuclear import and export of TR has emerged as a critical control point for modulating thyroid hormone-responsive gene expression; however, sequence motifs of TR that mediate shuttling are not fully defined. Here, we characterized multiple signals that direct TR shuttling. Along with the known nuclear localization signal in the hinge domain, we identified a novel nuclear localization signal in the A/B domain of thyroid hormone receptor a1 that is absent in thyroid hormone receptor B1 and inactive …