Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Biology

Western Michigan University

Research and Creative Activities Poster Day

Publication Year

Articles 1 - 4 of 4

Full-Text Articles in Life Sciences

Characterization Of A Neuroprotective Retinal Synapse After Inducing Glaucoma In Long Evans Rats, Cynthia A. Cooley-Themm Apr 2017

Characterization Of A Neuroprotective Retinal Synapse After Inducing Glaucoma In Long Evans Rats, Cynthia A. Cooley-Themm

Research and Creative Activities Poster Day

Glaucoma is a group of degenerative retinal diseases characterized by progressive loss of retinal ganglion cells (RGCs) and their axons leading to irreversible loss of vision. Neuroprotection has been defined as any intervention that prevents optic nerve damage or RGC death. The neurotransmitter, acetycholine (ACh), has been linked to neuroprotection against excitotoxic cell death and neurodegenerative diseases of the central nervous system (CNS). Results from our lab have demonstrated that ACh provides neuroprotection against glutamate-induced excitotoxicity in isolated pig and rat RGCs in vitro. Additional studies using an in vivo rat model of glaucoma have shown that intravitreal injections or …


To What Extent Is The Established Conceptual Framework Of Animal Behaviour Portrayed In Textbooks?, Andrea M. K. Bierema, Renee S. Schwartz Apr 2014

To What Extent Is The Established Conceptual Framework Of Animal Behaviour Portrayed In Textbooks?, Andrea M. K. Bierema, Renee S. Schwartz

Research and Creative Activities Poster Day

In 1963, Tinbergen revolutionized the study of animal behaviour by revamping the conceptual framework of the discipline. His framework suggests an integration of four questions: causation, ontogeny, survival value, and evolution. The National Research Council Committee on Undergraduate Biology Education to Prepare Research Scientists for the 21st Century (2003) suggests alignment between current research and undergraduate education. The purpose of this study, therefore, is to determine if the conceptual framework used by animal behaviour scientists, as presented in current primary literature, aligns with what students are exposed to in undergraduate biology education. After determining the most commonly listed textbooks from …


Gdnf's Expression In Slow- And Fast-Twitch Muscle Fibers Are Dependent On Exercise Intensity, Amy Morrison Gyorkos Apr 2013

Gdnf's Expression In Slow- And Fast-Twitch Muscle Fibers Are Dependent On Exercise Intensity, Amy Morrison Gyorkos

Research and Creative Activities Poster Day

No abstract provided.


Purkinje Cell Association With Microglia/Macrophages In Degenerating Cerebellum Of Multiple System Atrophy Patients, Ashley A. Mckinney Apr 2011

Purkinje Cell Association With Microglia/Macrophages In Degenerating Cerebellum Of Multiple System Atrophy Patients, Ashley A. Mckinney

Research and Creative Activities Poster Day

Multiple system atrophy (MSA) is a sporadic neurodegenerative disease with unknown etiology, involving Parkinson's disease, Autonomic Failure, and Olivopontocerebellar Atrophy (OPCA). To define a possible relationship between phagocytic immune cells and loss of Purkinje cells in MSA/OPCA, we measured the incidence of microglial/macrophages in close association with Purkinje cells and/or their axons and dendrites. Using immunocytochemistry methods on cerebellar sections from MSA and control brains from the New York Brain Bank at Columbia University, we identified Purkinje cells and their processes using anti-calbindin, and microglia/macrophages using anti-CD68. Calbindin labeled Purkinje cell body, axon, and dendritic profiles were counted in the …