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Full-Text Articles in Life Sciences

Exploring The Structure And Function Of The Snf1 Kinase Gene In The Slime Mold Dictyostelium Discoideum, Bryan Donald Whitemarsh May 1997

Exploring The Structure And Function Of The Snf1 Kinase Gene In The Slime Mold Dictyostelium Discoideum, Bryan Donald Whitemarsh

Undergraduate Honors Capstone Projects

All organisms must respond to different environmental stresses. For unicellular organisms, the most important source of stress is starvation or nutrient depletion. These microscopic life forms must respond to a constantly changing food supply in which short periods of nutrient availability are interspersed with extended periods of famine. In addition to complete starvation, these organisms are affected by other chemical changes, such as forced switching from a desirable to a less desirable carbon source, and physical changes, such as heat shock. Many microorganisms respond to such stresses by entering a different phase of their life cycle. For example, the budding …


The Role Of Cold Acclimatization On The Biogeography Of The Mountain Chickadee (Parus Gambeli) And The Juniper Titmouse (Parus Ridgwayi), Sheldon J. Cooper May 1997

The Role Of Cold Acclimatization On The Biogeography Of The Mountain Chickadee (Parus Gambeli) And The Juniper Titmouse (Parus Ridgwayi), Sheldon J. Cooper

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Biogeographic patterns of animals are shaped by biotic interactions, such as competition, and by abiotic factors, such as climate. Mountain Chickadees (Parus gambeli) and Juniper Titmice (Parus ridgway) are permanent residents of regions of western North America and are ecologically similar, but have different northern range limits. l measured several physiological variables, including basal metabolic rate (BMR), peak metabolic rate (PMR = maximal thermogenic capacity), metabolic response to varying environmental temperature (MRT), evaporative water loss (EWL), and daily energy expenditure (DEE) for summer-and winter-acclimatized Mountain Chickadees and Juniper Titmice to determine if seasonal and interspecific variation in cold tolerance and …


Evolutionary Genetics Of Canyon Treefrogs (Hyla Arenicolor), Roy A. Murray May 1997

Evolutionary Genetics Of Canyon Treefrogs (Hyla Arenicolor), Roy A. Murray

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Population genetics is the study of the mechanisms that cause genetic change in populations over time. Genetic changes may lead to both adaptive evolution and speciation. While the former process is fairly well understood, many questions remain unanswered with regard to the process of speciation. How important is population isolation in the process of speciation? How long must populations be isolated before speciation is complete? Are the genetic changes that take place during speciation caused mainly by natural selection or does genetic drift play a substantial role? Can genetic drift alone lead to reproductive isolation? These types of questions have …


Interaction Of The Human Serine Protease Inhibitor Alpha-1-Antitrypsin With Cryptosporidium Parvum, John Russell Forney May 1997

Interaction Of The Human Serine Protease Inhibitor Alpha-1-Antitrypsin With Cryptosporidium Parvum, John Russell Forney

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The human serine protease inhibitor (serpin) alpha-1-antitrypsin (AAT) was studied for potential interaction with components of the protozoan parasite Cryptosporidium parvum. A homogenate prepared from C. parvum oocysts was incubated with purified human AAT, and complexes formed between the serpin and components of the homogenate were detected using an enzyme-linked immunosorbent assay (ELISA). Serpin:parasite infections were effectively blocked by preincubating AAT with a cognate target enzyme, porcine pancreatic elastase, prior to performing the ELISA on the homogenate. Incubation of a mixture of C. parvum oocysts and sporozoites with AAT demonstrated preferential fluorescence labeling of the sporozoite surface membrane by indirect …