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- 02. My Life with Polymer Science (2)
- 19. How Pearls are made (2)
- 21. From the Congress in Vienna (Metternich) to the Pacific Polymer Federation (2)
- 22. Chirality and Handedness (2)
- 18. Degradadation, Aging and Stabilization (1)
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- 20. Solid State Chemical Reactions and Polymerizations (1)
- Apoptosis (1)
- Bcl-2 (1)
- Brachypodium distachyon (1)
- Brachyramphus brevirostris (1)
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- Competition (1)
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- Crystalline cellulose deposition (1)
- Crystallization and Polymerization (1)
- Deepwater Horizon (1)
- Drosophila (1)
- Embryonic development (1)
- Foraging ecology (1)
- Giant fiber (1)
- Guidance (1)
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- Kittlitz’s Murrelet (1)
- Lignin deposition (1)
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- Otto Vogl (1)
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Articles 1 - 18 of 18
Full-Text Articles in Life Sciences
Crystallization And Polymerization, Otto Vogl, Frank T. Traceski, Eric G. Vogl
Crystallization And Polymerization, Otto Vogl, Frank T. Traceski, Eric G. Vogl
Otto Vogl
No abstract provided.
Pictures From My Life With Polymer Science: Album 12, Otto Vogl
Pictures From My Life With Polymer Science: Album 12, Otto Vogl
Otto Vogl
No abstract provided.
Solid State Chemical Reactions And Polymerizations: The Initial Synthesis Of Dna?, Otto Vogl, Frank T. Traceski
Solid State Chemical Reactions And Polymerizations: The Initial Synthesis Of Dna?, Otto Vogl, Frank T. Traceski
Otto Vogl
A Proposal for Covering individual Macromolecules with Macromolecules including a Realistic Chiral Synthesis of Nucleic Acids.
Does The Precision Of A Biological Clock Depend Upon Its Period? Effects Of The Duper And Tau Mutations In Syrian Hamsters, Eric L. Bittman
Does The Precision Of A Biological Clock Depend Upon Its Period? Effects Of The Duper And Tau Mutations In Syrian Hamsters, Eric L. Bittman
Eric L. Bittman
Mutations which alter the feedback loops that generate circadian rhythms may provide insight into their insensitivity to perturbation robustness) and their consistency of period (precision). I examined relationships between endogenous period, activity and rest (τDD, α and ρ) in Syrian hamsters using two different mutations, duper and tau, both of which speed up the circadian clock. I generated 8 strains of hamsters that are homozygous or heterozygous for the tau, duper, and wild type alleles in all combinations. The endogenous period of activity onsets among these strains ranged from 17.94+0.04 to 24.13±0.04 h. Contrary to predictions, the variability of period …
Macondo Crude Oil From The Deepwater Horizon Oil Spill Disrupts Specific Developmental Processes During Zebrafish Embryogenesis, T Yvanka De Soysa, Allison Ulrich, Timo Friedrich, Danielle Pite, Shannon L. Compton, Deborah Ok, Rebecca L. Bernardos, Gerald B. Downes, Shizuka Hsieh, Rachael Stein, M Caterina Lagdameo, Katherine Halvorsen, Lydia-Rose Kesich, Michael Jf Barresi
Macondo Crude Oil From The Deepwater Horizon Oil Spill Disrupts Specific Developmental Processes During Zebrafish Embryogenesis, T Yvanka De Soysa, Allison Ulrich, Timo Friedrich, Danielle Pite, Shannon L. Compton, Deborah Ok, Rebecca L. Bernardos, Gerald B. Downes, Shizuka Hsieh, Rachael Stein, M Caterina Lagdameo, Katherine Halvorsen, Lydia-Rose Kesich, Michael Jf Barresi
Gerald B. Downes
Background: The Deepwater Horizon disaster was the largest marine oil spill in history, and total vertical exposure of oil to the water column suggests it could impact an enormous diversity of ecosystems. The most vulnerable organisms are those encountering these pollutants during their early life stages. Water-soluble components of crude oil and specific polycyclic aromatic hydrocarbons have been shown to cause defects in cardiovascular and craniofacial development in a variety of teleost species, but the developmental origins of these defects have yet to be determined. We have adopted zebrafish, Danio rerio, as a model to test whether water accumulated fractions …
Target Recognition And Competitive Synaptogenesis In The Drosophila Giant Fiber System, Jason Joseph Hill
Target Recognition And Competitive Synaptogenesis In The Drosophila Giant Fiber System, Jason Joseph Hill
Open Access Dissertations
The development of complex neural networks relies on a careful balance of environmental cues to guide and shape both ends of the eventual connection. However, the correct wiring of circuits whose components share molecular profiles depends on a more elaborate phenomenon, competition. Despite being highly studied, there is still a lack of understanding as to the mechanism that allows molecularly identical cells to form exclusive connections with their targets. To address this complex question, we turned to a simple circuit within the genetically tractable fly. Responsible for the escape reflex, the Giant Fiber System is comprised of bilaterally symmetrical axons …
Identification And Expression Analysis Of Methyl Jasmonate Responsive Ests In Paclitaxel Producing Taxus Cuspidata Suspension Culture Cells, Sangram K. Lenka, Nadia Boutaoui, Bibin Paulose, Kham Vongpaseuth, Jennifer Normanly, Susan C. Roberts, Elsbeth L. Walker
Identification And Expression Analysis Of Methyl Jasmonate Responsive Ests In Paclitaxel Producing Taxus Cuspidata Suspension Culture Cells, Sangram K. Lenka, Nadia Boutaoui, Bibin Paulose, Kham Vongpaseuth, Jennifer Normanly, Susan C. Roberts, Elsbeth L. Walker
Elsbeth Walker
Background Taxol(R)(paclitaxel) promotes microtubule assembly and stabilization and therefore is a potent chemotherapeutic agent against wide range of cancers. Methyl jasmonate (MJ) elicited Taxus cell cultures provide a sustainable option to meet the growing market demand for paclitaxel. Despite its increasing pharmaceutical importance, the molecular genetics of paclitaxel biosynthesis is not fully elucidated. This study focuses on identification of MJ responsive transcripts in cultured Taxus cells using PCR-based suppression subtractive hybridization (SSH) to identify genes involved in global pathway control. Results Six separate SSH cDNA libraries of paclitaxel-accumulating Taxus cuspidata P991 cell lines were constructed at three different post-elicitation time …
Transcriptional Regulation Of Grass Secondary Cell Wall Biosynthesis: Playing Catch-Up With Arabidopsis Thaliana, Pubudu P. Handakumbura, Samuel P. Hazen
Transcriptional Regulation Of Grass Secondary Cell Wall Biosynthesis: Playing Catch-Up With Arabidopsis Thaliana, Pubudu P. Handakumbura, Samuel P. Hazen
Samuel P Hazen
Secondary cell wall synthesis occurs in specialized cell types following completion of cell enlargement. By virtue of mechanical strength provided by a wall thickened with cellulose, hemicelluloses, and lignin, these cells can function as water-conducting vessels and provide structural support. Several transcription factor families regulate genes encoding wall synthesis enzymes. Certain NAC and MYB proteins directly bind to the SNBE and AC elements upstream of structural genes and other transcription factors. The most detailed model of this regulatory network is established predominantly for a eudicot, Arabidopsis thaliana. In grasses, both the patterning and the composition of secondary cell walls are …
Mutation Of Zebrafish Dihydrolipoamide Branched-Chain Transacylase E2 Results In Motor Dysfunction And Models Maple Syrup Urine Disease, Timo Friedrich, Aaron M. Lambert, Mark A. Masino, Gerald B. Downes
Mutation Of Zebrafish Dihydrolipoamide Branched-Chain Transacylase E2 Results In Motor Dysfunction And Models Maple Syrup Urine Disease, Timo Friedrich, Aaron M. Lambert, Mark A. Masino, Gerald B. Downes
Gerald B. Downes
Analysis of zebrafish mutants that demonstrate abnormal locomotive behavior can elucidate the molecular requirements for neural network function and provide new models of human disease. Here, we show that zebrafish quetschkommode (que) mutant larvae exhibit a progressive locomotor defect that culminates in unusual nose-to-tail compressions and an inability to swim. Correspondingly, extracellular peripheral nerve recordings show that que mutants demonstrate abnormal locomotor output to the axial muscles used for swimming. Using positional cloning and candidate gene analysis, we reveal that a point mutation disrupts the gene encoding dihydrolipoamide branched-chain transacylase E2 (Dbt), a component of a mitochondrial enzyme complex, to …
Biological Conversion Assay Using Clostridium Phytofermentans To Estimate Plant Feedstock Quality, Scott J. Lee, Thomas A. Warnick, Sivakumar Pattahil, Jesus G. Alvelo-Maurosa, Michelle J. Serapiglia, Heather Mccormick, Virginia Brown, Naomi F. Young, Danny J. Schnell, Lawrence B. Smart, Michael G. Hahn, Jeffrey F. Pedersen, Susan B. Leschine, Samuel P. Hazen
Biological Conversion Assay Using Clostridium Phytofermentans To Estimate Plant Feedstock Quality, Scott J. Lee, Thomas A. Warnick, Sivakumar Pattahil, Jesus G. Alvelo-Maurosa, Michelle J. Serapiglia, Heather Mccormick, Virginia Brown, Naomi F. Young, Danny J. Schnell, Lawrence B. Smart, Michael G. Hahn, Jeffrey F. Pedersen, Susan B. Leschine, Samuel P. Hazen
Samuel P Hazen
Background - There is currently considerable interest in developing renewable sources of energy. One strategy is the biological conversion of plant biomass to liquid transportation fuel. Several technical hurdles impinge upon the economic feasibility of this strategy, including the development of energy crops amenable to facile deconstruction. Reliable assays to characterize feedstock quality are needed to measure the effects of pre-treatment and processing and of the plant and microbial genetic diversity that influence bioconversion efficiency. Results - We used the anaerobic bacterium Clostridium phytofermentans to develop a robust assay for biomass digestibility and conversion to biofuels. The assay utilizes the …
Pictures From My Life With Polymer Science: Album 11, Otto Vogl
Pictures From My Life With Polymer Science: Album 11, Otto Vogl
Otto Vogl
No abstract provided.
Investigating The Mechanism Of Nur77-Induced Apoptosis In T Cells, Heather E. Fogarty
Investigating The Mechanism Of Nur77-Induced Apoptosis In T Cells, Heather E. Fogarty
Masters Theses 1911 - February 2014
Nur77 is a member of the orphan nuclear receptor family, where it is known to play an important role in apoptosis in both negative selection in T cells and in cancer cell lines. In the development of T cells, it is critical for the immune system to discriminate self from non-self by eliminating auto-reactive cells. It was originally thought that Nur77 initiated apoptosis by activating downstream gene targets. However, it is now clear that Nur77 has its own distinct role outside of the nucleus and the precise mechanisms by which Nur77 induces apoptosis in T cells still needs to be …
Population Size, Habitat Use And Diet Of Kittlitz's Murrelets In Prince William Sound, Alaska, Andrew J. Allyn
Population Size, Habitat Use And Diet Of Kittlitz's Murrelets In Prince William Sound, Alaska, Andrew J. Allyn
Masters Theses 1911 - February 2014
During the summer of 2008 and 2009, we studied the ecology of the Kittlitz’s Murrelet (Brachyramphus brevirostris), a small diving seabird and candidate for the U.S. Endangered Species List, in Prince William Sound (PWS), Alaska. At-sea survey data suggests that the population significantly increased from 2001 to 2009, however there is limited evidence of reproductive success. Habitat use models showed individuals were observed in shallower waters, closer to glaciers, the shoreline, and further from moraines than the available habitat during the daytime. Finer extent sampling from 2008 suggests temperature-depth profiles also influence Kittlitz’s Murrelet daytime habitat use. The …
Rhythmic Growth And Vascular Development In Brachypodium Distachyon, Dominick A. Matos
Rhythmic Growth And Vascular Development In Brachypodium Distachyon, Dominick A. Matos
Masters Theses 1911 - February 2014
Plants reduce inorganic carbon to synthesize biomass that is comprised of mostly polysaccharides and lignin. Growth is intricately regulated by external cues such as light, temperature, and water availability and internal cues including those generated by the circadian clock. While many aspects of polymer biosynthesis are known, their regulation and distribution within the stem are poorly understood. Plant biomass is perhaps the most abundant organic substance on Earth and can be used as feedstock for energy production. Various grass species are under development as energy crops yet several of their attributes make them challenging research subjects. Brachypodium distachyon has emerged …
Chirality And Handedness, Otto Vogl, Frank T. Traceski
Chirality And Handedness, Otto Vogl, Frank T. Traceski
Otto Vogl
No abstract provided.
How Pearls Are Made: A New Perspective, Otto Vogl
Degradadation, Aging And Stabilization, Otto Vogl
From The Congress In Vienna (Metternich) To The Pacific Polymer Federation, Otto Vogl, Frank T. Traceski
From The Congress In Vienna (Metternich) To The Pacific Polymer Federation, Otto Vogl, Frank T. Traceski
Otto Vogl
No abstract provided.