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Full-Text Articles in Life Sciences
Treatment Of Hiv-Infected Individuals With The Histone Deacetylase Inhibitor Panobinostat Results In Increased Numbers Of Regulatory T Cells And Limits Ex Vivo Lipopolysaccharide-Induced Inflammatory Responses, Christel Rothe Brinkmann, Jesper Falkesgaard Højen, Thomas Aagaard Rasmussen, Anne Sofie Kjær, Rikke Olesen, Paul W. Denton, Lars Østergaard, Zhengyu Ouyang, Mathias Lichterfeld, Xu Yu, Ole Schmeltz Søgaard, Charles Dinarello, Martin Tolstrup
Treatment Of Hiv-Infected Individuals With The Histone Deacetylase Inhibitor Panobinostat Results In Increased Numbers Of Regulatory T Cells And Limits Ex Vivo Lipopolysaccharide-Induced Inflammatory Responses, Christel Rothe Brinkmann, Jesper Falkesgaard Højen, Thomas Aagaard Rasmussen, Anne Sofie Kjær, Rikke Olesen, Paul W. Denton, Lars Østergaard, Zhengyu Ouyang, Mathias Lichterfeld, Xu Yu, Ole Schmeltz Søgaard, Charles Dinarello, Martin Tolstrup
Paul W. Denton
Histone deacetylase inhibitors (HDACi) modulate the transcriptional activity of all cells, including innate and adaptive immune cells. Therefore, we aimed to evaluate immunological effects of treatment with the HDACi panobinostat in HIV-infected patients during a clinical phase IIa latency reversal trial. Using flow cytometry, we investigated changes in T cell activation (CD69, CD38, HLA-DR) and the expression of CD39 and CTLA4 on regulatory T cells (Tregs). Whole-blood stimulations were performed and cytokine responses measured using Luminex. Gene expression in purified peripheral blood mononuclear cells (PBMCs) was evaluated using an Affymetrix HTA 2.0 gene chip. We found that proportions of CD4+ …
Tissue-Specific Transcriptome For Poeciliopsis Prolifica Reveals Evidence For Genetic Adaptation Related To The Evolution Of A Placental Fish, Nathaniel K. Jue, Robert J. Foley, David N. Reznick, Rachel J. O'Neill, Michael J. O'Neill
Tissue-Specific Transcriptome For Poeciliopsis Prolifica Reveals Evidence For Genetic Adaptation Related To The Evolution Of A Placental Fish, Nathaniel K. Jue, Robert J. Foley, David N. Reznick, Rachel J. O'Neill, Michael J. O'Neill
Nathaniel Jue
Transcriptome Analysis Reveals Potential Mechanisms Underlying Differential Heart Development In Fast- And Slow-Growing Broilers Under Heat Stress, Jibin Zhang, Carl J. Schmidt, Susan J. Lamont
Transcriptome Analysis Reveals Potential Mechanisms Underlying Differential Heart Development In Fast- And Slow-Growing Broilers Under Heat Stress, Jibin Zhang, Carl J. Schmidt, Susan J. Lamont
Jibin Zhang
Distinct Cardiac Responses To Heat Stress Between Two Broiler Lines Identified By Transcriptome Analysis, Jibin Zhang, Carl J. Schmidt, Susan J. Lamont
Distinct Cardiac Responses To Heat Stress Between Two Broiler Lines Identified By Transcriptome Analysis, Jibin Zhang, Carl J. Schmidt, Susan J. Lamont
Jibin Zhang
Differential Expression Of Cyb5a In Chinese And European Pig Breeds Due To Genetic Variations In The Promoter Region..Pdf, Ying Bai, Jibin Zhang, Y Xue, Yl Peng, Gang Chen, Meiying Fang
Differential Expression Of Cyb5a In Chinese And European Pig Breeds Due To Genetic Variations In The Promoter Region..Pdf, Ying Bai, Jibin Zhang, Y Xue, Yl Peng, Gang Chen, Meiying Fang
Jibin Zhang
Effect Of Environmental Factors On Whole Plant Assimilate Partitioning And Associated Gene Expression, Donald Geiger, K. Koch, Wen-Jang Shieh
Effect Of Environmental Factors On Whole Plant Assimilate Partitioning And Associated Gene Expression, Donald Geiger, K. Koch, Wen-Jang Shieh
Donald R. Geiger
Partitioning of assimilated carbon among sink organs is a critical factor that controls the rate and pattern of plant growth. Time-course measurements of plant and organ growth rates are useful for determining how regulation of carbon partitioning controls plantgrowth. Measuring growth rates over a 24 h period reveals the current pattern of carbon partitioning that can be used to predict growth ratesof specific sinks. Comparison of growth rates among sinks under defined conditions can point out key factors that regulate partitioning ofrecently assimilated carbon among sinks. Internal control of carbonpartitioning by developmental programmes regulates the timing andsite of carbon distribution …
Jibin Zhang's Ppt For Midwest Meeting.Pdf, Jibin Zhang, Yeunsu Suh, Young Min Choi, Michael E. Davis, Kichoon Lee
Jibin Zhang's Ppt For Midwest Meeting.Pdf, Jibin Zhang, Yeunsu Suh, Young Min Choi, Michael E. Davis, Kichoon Lee
Jibin Zhang