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Full-Text Articles in Life Sciences
(R2071) Global Stability Analysis Of Chikv Dynamics Model With Adaptive Immunity And Distributed Time Delays, Taofeek O. Alade, Samson Olaniyi, Hassan A. Idris, Yaqoob Al Rahbi, Mohammad Alnegga
(R2071) Global Stability Analysis Of Chikv Dynamics Model With Adaptive Immunity And Distributed Time Delays, Taofeek O. Alade, Samson Olaniyi, Hassan A. Idris, Yaqoob Al Rahbi, Mohammad Alnegga
Applications and Applied Mathematics: An International Journal (AAM)
The application of mathematical biology and dynamical systems has proven to be an effective approach for studying viral infection models. To contribute to this research, our paper proposes a new CHIKV model that takes into account an adaptive immune response and distributed time delays, which accurately reflects the time lag between initial viral contacts and the production of new active CHIKV particles. By analyzing the model’s qualitative behavior, we establish a biological threshold number that can predict whether CHIKV will be cleared from or persist in the body. We demonstrate the global stability of both CHIKV-present and CHIKV-free steady states …
(R1522) Modelling The Influence Of Desertic Aerosols On The Transmission Dynamics Of Neisseria Meningitidis Serogroup A, Francis Signing, Berge Tsanou, Samuel Bowong
(R1522) Modelling The Influence Of Desertic Aerosols On The Transmission Dynamics Of Neisseria Meningitidis Serogroup A, Francis Signing, Berge Tsanou, Samuel Bowong
Applications and Applied Mathematics: An International Journal (AAM)
This paper assesses the role of desert aerosols and vaccine on the transmission dynamics of Neisseria Meningitis serogroup A (NmA). It is biologically well-documented that the inhalation of aerosol dust and its presence in the nasal cavity weakens the nasopharyngeal mucosa by damaging the mucosal barrier and inhibiting the mucosal immune defenses of susceptible and vaccinated individuals. We address the latter by proposing and analyzing a mathematical model for the dynamics of NmA that specifically accounts for the fast progression of susceptible and vaccinated individuals to the invasive stage of the disease. We compute the basic reproduction number and use …
Global Stability Of Generalized Within-Host Chikungunya Virus Dynamics Models, Taofeek O. Alade, Afeez Abidemi, Cemil Tunç, Shafeek A. Ghaleb
Global Stability Of Generalized Within-Host Chikungunya Virus Dynamics Models, Taofeek O. Alade, Afeez Abidemi, Cemil Tunç, Shafeek A. Ghaleb
Applications and Applied Mathematics: An International Journal (AAM)
This paper proposes two models of a general nonlinear within-host Chikungunya virus (CHIKV) dynamics. The production, incidence, proliferation and removal rates of all compartments are modeled by general nonlinear functions that satisfy a set of reasonable conditions. The second model takes into consideration two forms of infected host cells: (i) latently infected cells which do not produce the CHIKV, (ii) actively infected cells which generate the CHIKV particles. We show that all the solutions of the models are nonnegative and bounded. The global stability of the steady states of the models is proven by applying Lyapunov method and LaSalle’s invariance …
Stability Of Delayed Virus Infection Model With A General Incidence Rate And Adaptive Immune Response, Zhimin Chen, Xiuxiang Liu, Zhongzhong Xie
Stability Of Delayed Virus Infection Model With A General Incidence Rate And Adaptive Immune Response, Zhimin Chen, Xiuxiang Liu, Zhongzhong Xie
Applications and Applied Mathematics: An International Journal (AAM)
We present the dynamical behaviors of a virus infection model with general infection rate, immune responses and two intracellular delays which describe the interactions of the HIV virus, target cells, CTL cells and antibodies within host. Three factors are incorporated in this model: (1) the intrinsic growth rate of uninfected cells, (2) a nonlinear incidence rate function considering both virus-tocell infection and cell-to-cell transmission, and (3) a nonlinear productivity and removal function. By the method of Lyapunov functionals and LaSalle’s invariance principle, we show that the global dynamics of the model is determined by the reproductive numbers for viral infection …
An Optimal Harvesting Strategy Of A Three Species Syn-Ecosystem With Commensalism And Stochasticity, M. N. Srinivas, A. Sabarmathi, K. S. Reddy, M. A. S. Srinivas
An Optimal Harvesting Strategy Of A Three Species Syn-Ecosystem With Commensalism And Stochasticity, M. N. Srinivas, A. Sabarmathi, K. S. Reddy, M. A. S. Srinivas
Applications and Applied Mathematics: An International Journal (AAM)
In this paper we have studied the stability of three typical species syn-ecosystem. The system comprises of one commensal S1 and two hosts S2 and S3 . Both S2 and S2 benefit S1 without getting themselves affected either positively or adversely. Further S2 is a commensal of S3 and S3 is a host of both S1 and S2. Limited resources have been considered for all the three species in this case. The model equations of the system constitute a set of three first order non-linear ordinary differential equations. …
Spread Of Malicious Objects In Computer Network: A Fuzzy Approach, Bimal K. Mishra, Apeksha Prajapati
Spread Of Malicious Objects In Computer Network: A Fuzzy Approach, Bimal K. Mishra, Apeksha Prajapati
Applications and Applied Mathematics: An International Journal (AAM)
We propose an e-epidemic fuzzy SEIQRS (Susceptible-Exposed-Infectious-Quarantine- Recovered-Susceptible) model for the transmission of malicious codes in a computer network. We have simulated the result for various parameters and analyzed the stability of the model. The efficiency of antivirus software and crashing of the nodes due to attack of malicious code is analyzed. Furthermore, initial simulation results illustrate the behavior of different classes for minimizing the infection in a computer network. It also reflects the positive impact of anti-virus software on malicious code propagation in a computer network. The basic reproduction number R0 f and its formulation is also discussed.
Global Dynamics Of A Water-Borne Disease Model With Multiple Transmission Pathways, Prasanta K. Mondal, T. K. Kar
Global Dynamics Of A Water-Borne Disease Model With Multiple Transmission Pathways, Prasanta K. Mondal, T. K. Kar
Applications and Applied Mathematics: An International Journal (AAM)
We propose and analyze a water born disease model introducing water-to-person and person-toperson transmission and saturated incidence. The disease-free equilibrium and the existence criterion of endemic equilibrium are investigated. Trans critical bifurcation at the disease-free equilibrium is obtained when the basic reproductive number is one. The local stability of both the equilibria is shown and a Lyapunov functional approach is also applied to explore the global stability of the system around the equilibria. We display the effects of pathogen contaminated water and infection through contact on the system dynamics in the absence of person-to-person contact as well as in the …