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Full-Text Articles in Life Sciences

Complete Genome Sequence Of Salinisphaera Sp. Strain Lb1, A Moderately Halo-Acidophilic Bacterium Isolated From Lake Brown, Western Australia, Kaela B. O'Dell, E. Anne Hatmaker, Adam M. Guss, Melanie R. Mormile Oct 2018

Complete Genome Sequence Of Salinisphaera Sp. Strain Lb1, A Moderately Halo-Acidophilic Bacterium Isolated From Lake Brown, Western Australia, Kaela B. O'Dell, E. Anne Hatmaker, Adam M. Guss, Melanie R. Mormile

Biological Sciences Faculty Research & Creative Works

Salinisphaera sp. strain LB1 was isolated from Lake Brown, Western Australia, surface water enriched at pH 4.0 and with 5% (wt/vol) NaCl. The complete genome sequence is presented in this report.


The Acyl-Coa Synthetase, Pudgy, Promotes Sleep And Is Required For The Homeostatic Response To Sleep Deprivation, Matthew S. Thimgan, Natlie Kress, John Lisse, Courtney Fiebelman, Thomas Hilderbrand Aug 2018

The Acyl-Coa Synthetase, Pudgy, Promotes Sleep And Is Required For The Homeostatic Response To Sleep Deprivation, Matthew S. Thimgan, Natlie Kress, John Lisse, Courtney Fiebelman, Thomas Hilderbrand

Biological Sciences Faculty Research & Creative Works

The regulation of sleep and the response to sleep deprivation rely on multiple biochemical pathways. A critical connection is the link between sleep and metabolism. Metabolic changes can disrupt sleep, and conversely decreased sleep can alter the metabolic environment. There is building evidence that lipid metabolism, in particular, is a critical part of mounting the homeostatic response to sleep deprivation. We have evaluated an acyl-CoA synthetase, pudgy (pdgy), for its role in sleep and response to sleep deprivation. When pdgytranscript levels are decreased through transposable element disruption of the gene, mutant flies showed lower total sleep times …


The Zinc Transporter Zipt-7.1 Regulates Sperm Activation In Nematodes, Yanmei Zhao, Chieh Hsiang Tan, Amber Krauchunas, Andrea Scharf, Nicholas Dietrich, Kurt Warnhoff, Zhiheng Yuan, Marina Druzhinina, Sam Guoping Gu, Long Miao, Andrew Singson, Ronald E. Ellis, Kerry Kornfeld Jun 2018

The Zinc Transporter Zipt-7.1 Regulates Sperm Activation In Nematodes, Yanmei Zhao, Chieh Hsiang Tan, Amber Krauchunas, Andrea Scharf, Nicholas Dietrich, Kurt Warnhoff, Zhiheng Yuan, Marina Druzhinina, Sam Guoping Gu, Long Miao, Andrew Singson, Ronald E. Ellis, Kerry Kornfeld

Biological Sciences Faculty Research & Creative Works

Sperm activation is a fascinating example of cell differentiation, in which immotile spermatids undergo a rapid and dramatic transition to become mature, motile sperm. Because the sperm nucleus is transcriptionally silent, this transition does not involve transcriptional changes. Although Caenorhabditis elegans is a leading model for studies of sperm activation, the mechanisms by which signaling pathways induce this transformation remain poorly characterized. Here we show that a conserved transmembrane zinc transporter, ZIPT-7.1, regulates the induction of sperm activation in Caenorhabditis nematodes. The zipt-7.1 mutant hermaphrodites cannot self-fertilize, and males reproduce poorly, because mutant spermatids are defective in responding to activating …


Heterogeneous Activity Causes A Nonlinear Increase In The Group Energy Use Of Ant Workers Isolated From Queen And Brood, Nolan Ferral, Kyara Holloway, Mingzhong Li, Zhaozheng Yin, Chen Hou Jun 2018

Heterogeneous Activity Causes A Nonlinear Increase In The Group Energy Use Of Ant Workers Isolated From Queen And Brood, Nolan Ferral, Kyara Holloway, Mingzhong Li, Zhaozheng Yin, Chen Hou

Computer Science Faculty Research & Creative Works

Increasing evidence has shown that the energy use of ant colonies increases sublinearly with colony size so that large colonies consume less per capita energy than small colonies. It has been postulated that social environment (e.g., in the presence of queen and brood) is critical for the sublinear group energetics, and a few studies of ant workers isolated from queens and brood observed linear relationships between group energetics and size. In this paper, we hypothesize that the sublinear energetics arise from the heterogeneity of activity in ant groups, that is, large groups have relatively more inactive members than small groups. …


Introducing The Jmbe Themed Issue On Science Communication, Dennis F. Mangan, Emily T. Cloyd, Jesus A. Romo, David R. Wessner, David J. Westenberg, For Full List Of Authors, See Publisher's Website. Mar 2018

Introducing The Jmbe Themed Issue On Science Communication, Dennis F. Mangan, Emily T. Cloyd, Jesus A. Romo, David R. Wessner, David J. Westenberg, For Full List Of Authors, See Publisher's Website.

Biological Sciences Faculty Research & Creative Works

No abstract provided.


Untangling The Effects Of Biosynthetic And Metabolic Rates On Oxidative Cellular Damage In An Insect Model, Nikki Jihui Gomez Jan 2018

Untangling The Effects Of Biosynthetic And Metabolic Rates On Oxidative Cellular Damage In An Insect Model, Nikki Jihui Gomez

Masters Theses

“Previously, a theoretical model for unravelling the entwined effects of metabolic and biosynthetic rates on oxidative cellular damage accumulation during an animal’s growth period was developed and tested in hornworms (Manduca sexta larvae). In theory, if an animal had unrestricted amounts of energy and a high repair efficiency, they could repair most of the oxidative cellular damage accumulated, regardless of how their metabolic rate varies. However, organisms have a finite amount of energy that is allocated to repair and, during the animal’s development period, a considerable amount of energy goes towards growth eliciting a tradeoff between biosynthesis and repair. …


Fluid Flow In A Krogh Cylinder: A Model For A Single Capillary And Surrounding Tissue, Xianjie Qiu Jan 2018

Fluid Flow In A Krogh Cylinder: A Model For A Single Capillary And Surrounding Tissue, Xianjie Qiu

Masters Theses

"A model describing the flow of plasma from the capillaries to the interstitial space in the extravascular tissue and back into the capillaries is constructed and solved. The flow through the tissue or the interstitial spaces is described by the Brinkman equation for porous medium, modified to account for the presence of cells considered as spheres. The flow of blood through the capillaries is considered to be that of a Newtonian fluid. The flow between capillary and tissue is coupled by the permeability of the capillary wall. The nature of flow and its magnitude was found to be highly dependent …


Comparative Toxicology Of Nio And Ni(Oh)₂ Nanoparticles, Melissa Hope Cambre Jan 2018

Comparative Toxicology Of Nio And Ni(Oh)₂ Nanoparticles, Melissa Hope Cambre

Masters Theses

“Understanding the potential toxicity of nanoparticles (NPs) is important to ensure that these new products do not impose harmful effects to human and environmental health. Paper I is a literature review in which we discuss characteristics of nanomaterials, with an emphasis on transition metal oxide nanoparticles that influence cytotoxicity. Identification of those properties may lead to the design of more efficient and safer nanosized products for various industrial purposes and provide guidance for assessment of human and environmental health risk. We then investigate biochemical and molecular mechanisms of cytotoxicity that include oxidative stress-induced cellular events and alteration of the pathways …