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Long-Term Recovery From Acute Cold Shock In Caenorhabditis Elegans, Joseph D. Robinson, Jennifer R. Powell
Long-Term Recovery From Acute Cold Shock In Caenorhabditis Elegans, Joseph D. Robinson, Jennifer R. Powell
Biology Faculty Publications
Background
Animals are exposed to a wide range of environmental stresses that can cause potentially fatal cellular damage. The ability to survive the period of stress as well as to repair any damage incurred is essential for fitness. Exposure to 2 °C for 24 h or longer is rapidly fatal to the nematode Caenorhabditis elegans, but the process of recovery from a shorter, initially non-lethal, cold shock is poorly understood.
Results
We report that cold shock of less than 12-hour duration does not initially kill C. elegans, but these worms experience a progression of devastating phenotypes over the …